SGCZ_HUMAN » Zeta-sarcoglycan

SGCZ_HUMAN » Zeta-sarcoglycan
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SGCZ_HUMAN » Zeta-sarcoglycan » Zeta-SG; ZSG1;
Hydrophobic Thickness 35.6 ± 2.6 Å
Tilt Angle 0 ± 2°
ΔGtransfer -52.3 kcal/mol
ΔGfold -21.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 28-59 (28-61)
Pathways none
PDB none
OPM none
Complexes none
Interactions

SGCB, Complex: SGCB:SGCZ, PubMed

Domains

AA: 25-285, Sarcoglycan complex subunit protein

UniProt annotation for SGCZ_HUMAN » Zeta-sarcoglycan
FUNCTION: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May play a role in the maintenance of striated muscle membrane stability (By similarity).
UniProt features for SGCZ_HUMAN » Zeta-sarcoglycan
CHAIN 1 299 Zeta-sarcoglycan.
DISULFID 273 289 Potential.
Amino Acid Sequence for SGCZ_HUMAN » Zeta-sarcoglycan
MTREQYILAT QQNNLPRTEN AQLYPVGIYG WRKRCLYFFV LLLLVTMIVN LAMTIWILKV MNFTVDGMGN LRVTKKGIRL EGISEFLLPL YVKEIHSRKD SPLVLQSDRN VTVNARNHMG QLTGQLTIGA DAVEAQCKRF EVRASEDGRV LFSADEDEIT IGAEKLKVTG TEGAVFGHSV ETPHIRAEPS QDLRLESPTR SLIMEAPRGV QVSAAAGDFK ATCRKELHLQ STEGEIFLNA ETIKLGNLPT GSFSSSSPSS SSSRQTVYEL CVCPNGKLYL SPAGVGSTCQ SSSNICLWS