SERK4_ARATH » Somatic embryogenesis receptor kinase 4

SERK4_ARATH » Somatic embryogenesis receptor kinase 4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SERK4_ARATH » Somatic embryogenesis receptor kinase 4 » AtSERK4; Protein BAK1-like 1;AtBKK1; Somatic embryogenesis receptor-like kinase 2;
Hydrophobic Thickness 34.8 ± 5.0 Å
Tilt Angle 30 ± 12°
ΔGtransfer -19.8 kcal/mol
ΔGfold -21.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 230-256 (227-258)
Pathways

Plant-pathogen interaction (KEGG)

PDB none
OPM none
Complexes none
Interactions

BRI1, Complex: BRI1:SERK4, PubMed

Y5838, Complex: SERK4:Y5838, PubMed

Domains

AA: 29-72, PDBID: 4M7E, Subunit D, Seq Identity:84%, Leucine rich repeat N-terminal domain

AA: 171-195, PDBID: 4M7E, Subunit C, Seq Identity:84%, Leucine Rich Repeat

AA: 294-568, PDBID: 3TL8, Subunit A, Seq Identity:94%, Protein kinase domain

UniProt annotation for SERK4_ARATH » Somatic embryogenesis receptor kinase 4
FUNCTION: Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Positively regulates the BR- dependent plant growth pathway and negatively regulates the BR- independent cell-death pathway.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

SUBUNIT: Interacts with the EF-Tu receptor EFR and FLS2 in a specific ligand-induced manner.

UniProt features for SERK4_ARATH » Somatic embryogenesis receptor kinase 4
SIGNAL 1 33 Potential.
CHAIN 34 620 Somatic embryogenesis receptor kinase 4.
REPEAT 100 122 LRR 1.
REPEAT 124 146 LRR 2.
REPEAT 148 170 LRR 3.
REPEAT 171 193 LRR 4.
REPEAT 194 215 LRR 5.
DOMAIN 294 591 Protein kinase.
ACT_SITE 421 421 Proton acceptor (By similarity).
Amino Acid Sequence for SERK4_ARATH » Somatic embryogenesis receptor kinase 4
MTSSKMEQRS LLCFLYLLLL FNFTLRVAGN AEGDALTQLK NSLSSGDPAN NVLQSWDATL VTPCTWFHVT CNPENKVTRV DLGNAKLSGK LVPELGQLLN LQYLELYSNN ITGEIPEELG DLVELVSLDL YANSISGPIP SSLGKLGKLR FLRLNNNSLS GEIPMTLTSV QLQVLDISNN RLSGDIPVNG SFSLFTPISF ANNSLTDLPE PPPTSTSPTP PPPSGGQMTA AIAGGVAAGA ALLFAVPAIA FAWWLRRKPQ DHFFDVPAEE DPEVHLGQLK RFTLRELLVA TDNFSNKNVL GRGGFGKVYK GRLADGNLVA VKRLKEERTK GGELQFQTEV EMISMAVHRN LLRLRGFCMT PTERLLVYPY MANGSVASCL RERPEGNPAL DWPKRKHIAL GSARGLAYLH DHCDQKIIHR DVKAANILLD EEFEAVVGDF GLAKLMNYND SHVTTAVRGT IGHIAPEYLS TGKSSEKTDV FGYGVMLLEL ITGQKAFDLA RLANDDDIML LDWVKEVLKE KKLESLVDAE LEGKYVETEV EQLIQMALLC TQSSAMERPK MSEVVRMLEG DGLAERWEEW QKEEMPIHDF NYQAYPHAGT DWLIPYSNSL IENDYPSGPR