SERK2_ARATH » Somatic embryogenesis receptor kinase 2

SERK2_ARATH » Somatic embryogenesis receptor kinase 2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SERK2_ARATH » Somatic embryogenesis receptor kinase 2 » AtSERK2; Somatic embryogenesis receptor-like kinase 2;
Hydrophobic Thickness 40.8 ± 1.4 Å
Tilt Angle 0 ± 1°
ΔGtransfer -33.0 kcal/mol
ΔGfold -18.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 240-264 (237-269)
Pathways none
PDB none
OPM none
Complexes none
Interactions

SERK1, Complex: SERK2:SERK1

Y5838, Complex: SERK2:Y5838, PubMed

Domains

AA: 29-69, PDBID: 4LSC, Subunit A, Seq Identity:88%, Leucine rich repeat N-terminal domain

AA: 169-194, PDBID: 4M7E, Subunit C, Seq Identity:69%, Leucine Rich Repeat

AA: 305-579, PDBID: 3TL8, Subunit A, Seq Identity:98%, Protein kinase domain

UniProt annotation for SERK2_ARATH » Somatic embryogenesis receptor kinase 2
FUNCTION: Serine/threonine-kinase involved in brassinosteroid- dependent and -independent signaling pathways. Acts redundantly with SERK1 as a control point for sporophytic development controlling male gametophyte production.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Homo- and heterodimer. Component of the SERK1 signaling complex, composed of KAPP, CDC48A, GRF6 or GRF7, SERK1, SERK2, SERK3/BAK1 and BRI1 (By similarity). Interacts with the EF-Tu receptor EFR and FLS2 in a specific ligand-induced manner.

TISSUE SPECIFICITY: Expressed in flowers, tapetum, developing microspores, all cells of the embryo sac, provascular strands and developing vascular bundles. Low expression in adult vascular tissue.

UniProt features for SERK2_ARATH » Somatic embryogenesis receptor kinase 2
SIGNAL 1 29 Potential.
CHAIN 30 628 Somatic embryogenesis receptor kinase 2.
REPEAT 97 120 LRR 1.
REPEAT 121 143 LRR 2.
REPEAT 145 166 LRR 3.
REPEAT 169 191 LRR 4.
DOMAIN 305 592 Protein kinase.
ACT_SITE 432 432 Proton acceptor (By similarity).
Amino Acid Sequence for SERK2_ARATH » Somatic embryogenesis receptor kinase 2
MGRKKFEAFG FVCLISLLLL FNSLWLASSN MEGDALHSLR ANLVDPNNVL QSWDPTLVNP CTWFHVTCNN ENSVIRVDLG NADLSGQLVP QLGQLKNLQY LELYSNNITG PVPSDLGNLT NLVSLDLYLN SFTGPIPDSL GKLFKLRFLR LNNNSLTGPI PMSLTNIMTL QVLDLSNNRL SGSVPDNGSF SLFTPISFAN NLDLCGPVTS RPCPGSPPFS PPPPFIPPPI VPTPGGYSAT GAIAGGVAAG AALLFAAPAL AFAWWRRRKP QEFFFDVPAE EDPEVHLGQL KRFSLRELQV ATDSFSNKNI LGRGGFGKVY KGRLADGTLV AVKRLKEERT PGGELQFQTE VEMISMAVHR NLLRLRGFCM TPTERLLVYP YMANGSVASC LRERPPSQLP LAWSIRQQIA LGSARGLSYL HDHCDPKIIH RDVKAANILL DEEFEAVVGD FGLARLMDYK DTHVTTAVRG TIGHIAPEYL STGKSSEKTD VFGYGIMLLE LITGQRAFDL ARLANDDDVM LLDWVKGLLK EKKLEMLVDP DLQSNYTEAE VEQLIQVALL CTQSSPMERP KMSEVVRMLE GDGLAEKWDE WQKVEVLRQE VELSSHPTSD WILDSTDNLH AMELSGPR