- Protein Classification
- Protein Complexes
- Species Selection
 | Golgi lumenal side |
| cytoplasmic side |
| SED5_YEAST » Integral membrane protein SED5 » | |
|---|---|
| Hydrophobic Thickness | 26.8 ± 2.6 Å |
| Tilt Angle | 3 ± 0° |
| ΔGtransfer | -35.8 kcal/mol |
| ΔGfold | -16.4 kcal/mol |
| Links | UniProtKB, Pfam, Interpro, iHOP, STRING |
| Topology | In |
| TM Segments | 320-339 (318-340) |
| Pathways | |
| PDB | 1mqs (B=1-45), 1pd0 (B=201-210) |
| OPM | none |
| Complexes | none |
| Interactions | ANP1, Complex: SED5:ANP1, PubMed ATG27, Complex: SED5:ATG27, PubMed BET1, Complex: SED5:BET1, PubMed BOS1, Complex: SED5:BOS1, PubMed EMP24, Complex: SED5:EMP24, PubMed EMP47, Complex: SED5:EMP47, PubMed ERP1, Complex: SED5:ERP1, PubMed ERP2, Complex: SED5:ERP2, PubMed ERP3, Complex: ERP3:SED5 GOSR1, Complex: SED5:GOSR1, PubMed HOC1, Complex: SED5:HOC1, PubMed KEX2, Complex: SED5:KEX2, PubMed KRE2, Complex: SED5:KRE2, PubMed KTR1, Complex: SED5:KTR1, PubMed KTR3, Complex: SED5:KTR3, PubMed KTR4, Complex: SED5:KTR4, PubMed MNN10, Complex: SED5:MNN10, PubMed MNN11, Complex: SED5:MNN11, PubMed MNN2, Complex: SED5:MNN2, PubMed MNN9, Complex: SED5:MNN9, PubMed NYV1, Complex: SED5:NYV1, PubMed PEP12, Complex: SED5:PEP12, PubMed SEC22, Complex: SED5:SEC22, PubMed SEC66, Complex: SED5:SEC66, PubMed SFT1, Complex: SED5:SFT1, PubMed SNC2, Complex: SED5:SNC2, PubMed TLG1, Complex: SED5:TLG1, PubMed TLG2, Complex: SED5:TLG2 TMEDA, Complex: SED5:TMEDA, PubMed UFE1, Complex: UFE1:SED5 USE1, Complex: SED5:USE1 |
| Domains | AA: 1-20, PDBID: 1MQS, Subunit B, Seq Identity:100%, Syntaxin-5 N-terminal, Sly1p-binding domain AA: 285-337, PDBID: 5BUZ, Subunit C, Seq Identity:29%, SNARE domain |
| UniProt annotation for SED5_YEAST » Integral membrane protein SED5 |
|---|
| FUNCTION: Required for vesicular transport between the endoplasmic reticulum and the Golgi complex. Acts as a target organelle soluble NSF attachment protein receptor (t-SNARE). SUBUNIT: Interacts with SLY1, STF1, SFB3 and GOS1. MISCELLANEOUS: Present with 300 molecules/cell in log phase SD medium. |
| UniProt features for SED5_YEAST » Integral membrane protein SED5 |
|---|
|
CHAIN 1 340 Integral membrane protein SED5. DOMAIN 249 311 t-SNARE coiled-coil homology. COILED 146 173 Potential. |
| Amino Acid Sequence for SED5_YEAST » Integral membrane protein SED5 |
|---|
| MNIKDRTSEF QQSVLSYKKR NKNFREQQRE RLQEKESENF ANNTTGNGKS VSEFQKKASG IAHEISSTAQ LLSKLAVLAK RKPMFNDNPV EIAELSFLIK RKIYAIEQSL VQLSQLKKTD VNGNTSNQSS KQPSAVQHSK NVVNLLNTQM KNISGSFKDV LEERQRLEMA NKDRWQKLTT DTGHAPADDQ TQSNHAADLT TYNNSNPFMT SLLDESSEKN NNSSNQGELS FPQNDSQLML MEEGQLSNNV YLQERNRAVE TIESTIQEVG NLFQQLASMV QEQGEVIQRI DANVDDIDLN ISGAQRELLK YFDRIKSNRW LAAKVFFIIF VFFVIWVLVN |
