SECE_METJA » Preprotein translocase subunit SecE

SECE_METJA » Preprotein translocase subunit SecE
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Topology in Archaebacterial membrane
Topologyextracellular side
cytoplasmic side
SECE_METJA » Preprotein translocase subunit SecE » Protein transport protein Sec61 gamma subunit homolog;
Hydrophobic Thickness 31.2 ± 3.5 Å
Tilt Angle 12 ± 11°
ΔGtransfer -15.3 kcal/mol
ΔGfold -10.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 34-55 (31-57)
Pathways

Bacterial secretion system (KEGG)

Protein export (KEGG)

PDB 4v4n (1-67), 3bo0 (28-67), 3bo1 (28-67), 4v7i (28-67), 3dkn (3-67), 1rh5 (B=1-74), 1rhz (B=1-74), 2yxq (B=1-74), 2yxr (B=1-74)
OPM 1rh5, 1rhz, 2yxq, 2yxr, 2zjs (THET8), 2zqp (THET8), 3bo0, 3din (THEMA), 3dkn, 3j45 (ECOLI), 3j46 (ECOLI), 3mp7 (PYRFU)
Complexes

SECE:SECY:SECG:SECA_AQUAE

SECE:SECG:SECY_ECOLI

SECG:SECE:SECY_METJA

Interactions

SECG, Complex: SECG:SECE:SECY, PDBID: 1RH5

Domains none
UniProt annotation for SECE_METJA » Preprotein translocase subunit SecE
FUNCTION: Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

SUBUNIT: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.

UniProt features for SECE_METJA » Preprotein translocase subunit SecE
CHAIN 1 74 Preprotein translocase subunit SecE.
Amino Acid Sequence for SECE_METJA » Preprotein translocase subunit SecE
MKTDFNQKIE QLKEFIEECR RVWLVLKKPT KDEYLAVAKV TALGISLLGI IGYIIHVPAT YIKGILKPPT TPRV