SD113_ARATH » G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13

SD113_ARATH » G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SD113_ARATH » G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13 » Calmodulin-binding receptor-like protein kinase 1;Receptor-like protein kinase 2;S-domain-1 (SD1) receptor kinase 13;SD1-13;
Hydrophobic Thickness 39.2 ± 5.4 Å
Tilt Angle 28 ± 21°
ΔGtransfer -31.2 kcal/mol
ΔGfold -24.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 431-460 (425-462)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: SD113:BETL2

CRK40, Complex: SD113:CRK40

PAM74, Complex: SD113:PAM74

UBC32, Complex: SD113:UBC32

UBC34, Complex: SD113:UBC34

WAK3, Complex: SD113:WAK3

Domains

AA: 69-178, PDBID: 4OIT, Subunit C, Seq Identity:13%, D-mannose binding lectin

AA: 208-319, S-locus glycoprotein domain

AA: 340-408, PAN-like domain

AA: 512-783, PDBID: 1UWH, Subunit B, Seq Identity:43%, Protein tyrosine kinase

AA: 785-830, Domain of unknown function (DUF3403)

UniProt annotation for SD113_ARATH » G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13
FUNCTION: Receptor-like serine/threonine-protein kinase that represses the disease resistance signaling pathway triggered in response to bacterial pathogen such as Pseudomonas syringae pv. tomato.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Interacts with PUB9, PUB13 and PUB14. Binds to calmodulin (CaM) in a Ca(2+)-dependent manner.

TISSUE SPECIFICITY: Mostly expressed in rosette leaves, and, to a lower extent, in cauline leaves and stems.

INDUCTION: By P.syringae and salicylic acid (SA).

UniProt features for SD113_ARATH » G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13
SIGNAL 1 21 Potential.
CHAIN 22 830 G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13.
DOMAIN 22 145 Bulb-type lectin.
DOMAIN 283 321 EGF-like; atypical.
DOMAIN 340 423 PAN.
DOMAIN 512 798 Protein kinase.
REGION 601 618 CaM-binding.
ACT_SITE 637 637 Proton acceptor (By similarity).
DISULFID 287 299 By similarity.
DISULFID 293 309 By similarity.
DISULFID 377 398 By similarity.
DISULFID 381 387 By similarity.
Amino Acid Sequence for SD113_ARATH » G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13
MGCLLILLLT LICFSLRLCL ATDVITFSSE FRDSETVVSN HSTFRFGFFS PVNSTGRYAG IWFNNIPVQT VVWVANSNSP INDSSGMVSI SKEGNLVVMD GRGQVHWSTN VLVPVAANTF YARLLNTGNL VLLGTTNTGD EILWESFEHP QNIYLPTMSL ATDTKTGRSL KLRSWKSPFD PSPGRYSAGL IPLPFPELVV WKDDLLMWRS GPWNGQYFIG LPNMDYRINL FELTLSSDNR GSVSMSYAGN TLLYHFLLDS EGSVFQRDWN VAIQEWKTWL KVPSTKCDTY ATCGQFASCR FNPGSTPPCM CIRGFKPQSY AEWNNGNWTQ GCVRKAPLQC ESRDNNDGSR KSDGFVRVQK MKVPHNPQRS GANEQDCPES CLKNCSCTAY SFDRGIGCLL WSGNLMDMQE FSGTGVVFYI RLADSEFKKR TNRSIVITVT LLVGAFLFAG TVVLALWKIA KHREKNRNTR LLNERMEALS SNDVGAILVN QYKLKELPLF EFQVLAVATN NFSITNKLGQ GGFGAVYKGR LQEGLDIAVK RLSRTSGQGV EEFVNEVVVI SKLQHRNLVR LLGFCIEGEE RMLVYEFMPE NCLDAYLFDP VKQRLLDWKT RFNIIDGICR GLMYLHRDSR LKIIHRDLKA SNILLDENLN PKISDFGLAR IFQGNEDEVS TVRVVGTYGY MAPEYAMGGL FSEKSDVFSL GVILLEIVSG RRNSSFYNDG QNPNLSAYAW KLWNTGEDIA LVDPVIFEEC FENEIRRCVH VGLLCVQDHA NDRPSVATVI WMLSSENSNL PEPKQPAFIP RRGTSEVESS GQSDPRASIN NVSLTKITGR