SCO2_YEAST » Protein SCO2, mitochondrial

SCO2_YEAST » Protein SCO2, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
SCO2_YEAST » Protein SCO2, mitochondrial »
Hydrophobic Thickness 26.8 ± 1.3 Å
Tilt Angle 12 ± 7°
ΔGtransfer -15.1 kcal/mol
ΔGfold -8.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 78- 97 (76-101)
Pathways none
PDB none
OPM none
Complexes none
Interactions

AIM18, Complex: AIM18:SCO2

FCJ1, Complex: SCO2:FCJ1, PubMed

MGR3, Complex: MGR3:SCO2

PNT1, Complex: SCO2:PNT1

SCO1, Complex: SCO1:SCO2, PubMed

Domains

AA: 84-267, PDBID: 2B7J, Subunit C, Seq Identity:65%, SCO1/SenC

UniProt annotation for SCO2_YEAST » Protein SCO2, mitochondrial
FUNCTION: Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2).

MISCELLANEOUS: Present with 1480 molecules/cell in log phase SD medium.

UniProt features for SCO2_YEAST » Protein SCO2, mitochondrial
TRANSIT 1 ? Mitochondrion (Potential).
CHAIN ? 301 Protein SCO2, mitochondrial.
DOMAIN 101 284 Thioredoxin.
Amino Acid Sequence for SCO2_YEAST » Protein SCO2, mitochondrial
MLNSSRKYAC RSLFRQANVS IKGLFYNGGA YRRGFSTGCC LRSDNKESPS ARQPLDRLQL GDEINEPEPI RTRFFQFSRW KATIALLLLS GGTYAYLSRK RRLLETEKEA DANRAYGSVA LGGPFNLTDF NGKPFTEENL KGKFSILYFG FSHCPDICPE ELDRLTYWIS ELDDKDHIKI QPLFISCDPA RDTPDVLKEY LSDFHPAIIG LTGTYDQVKS VCKKYKVYFS TPRDVKPNQD YLVDHSIFFY LIDPEGQFID ALGRNYDEQS GLEKIREQIQ AYVPKEERER RSKKWYSFIF N