SCO1_YEAST » Protein SCO1, mitochondrial

SCO1_YEAST » Protein SCO1, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
SCO1_YEAST » Protein SCO1, mitochondrial »
Hydrophobic Thickness 29.0 ± 3.0 Å
Tilt Angle 11 ± 0°
ΔGtransfer -17.8 kcal/mol
ΔGfold -12.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 71-91 (68-96)
Pathways none
PDB 2b7j (96-295), 2b7k (96-295)
OPM none
Complexes none
Interactions

ATP18, Complex: ATP18:SCO1

COX11, Complex: COX11:SCO1

MRL1, Complex: SCO1:MRL1, PubMed

SCO2, Complex: SCO1:SCO2, PubMed

Domains

AA: 77-261, PDBID: 2B7J, Subunit C, Seq Identity:100%, SCO1/SenC

UniProt annotation for SCO1_YEAST » Protein SCO1, mitochondrial
FUNCTION: Required for the accumulation of subunits 1 and 2 of cytochrome c oxidase complex. Thought to play a role in either mitochondrial copper transport or insertion of copper into the active site of COX.

MISCELLANEOUS: Present with 2550 molecules/cell in log phase SD medium.

UniProt features for SCO1_YEAST » Protein SCO1, mitochondrial
TRANSIT 1 ? Mitochondrion (Potential).
CHAIN ? 295 Protein SCO1, mitochondrial.
Amino Acid Sequence for SCO1_YEAST » Protein SCO1, mitochondrial
MLKLSRSANL RLVQLPAARL SGNGAKLLTQ RGFFTVTRLW QSNGKKPLSR VPVGGTPIKD NGKVREGSIE FSTGKAIALF LAVGGALSYF FNREKRRLET QKEAEANRGY GKPSLGGPFH LEDMYGNEFT EKNLLGKFSI IYFGFSNCPD ICPDELDKLG LWLNTLSSKY GITLQPLFIT CDPARDSPAV LKEYLSDFHP SILGLTGTFD EVKNACKKYR VYFSTPPNVK PGQDYLVDHS IFFYLMDPEG QFVDALGRNY DEKTGVDKIV EHVKSYVPAE QRAKQKEAWY SFLFK