SCO12_ARATH » Protein SCO1 homolog 2, mitochondrial

SCO12_ARATH » Protein SCO1 homolog 2, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
SCO12_ARATH » Protein SCO1 homolog 2, mitochondrial » Homolog of the copper chaperone SCO1 member 2;HCC2;
Hydrophobic Thickness 31.0 ± 3.4 Å
Tilt Angle 12 ± 9°
ΔGtransfer -15.6 kcal/mol
ΔGfold -10.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 64-85 (60-90)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 102-259, PDBID: 4TXO, Subunit D, Seq Identity:45%, SCO1/SenC

UniProt annotation for SCO12_ARATH » Protein SCO1 homolog 2, mitochondrial
FUNCTION: Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX (By similarity). Participates in copper and redox homeostasis.

TISSUE SPECIFICITY: Expressed in the whole plant with highest expression in imbibed seeds and embryos, and the root hair zone.

UniProt features for SCO12_ARATH » Protein SCO1 homolog 2, mitochondrial
TRANSIT 1 14 Mitochondrion (Potential).
CHAIN 15 276 Protein SCO1 homolog 2, mitochondrial.
DOMAIN 110 273 Thioredoxin.
Amino Acid Sequence for SCO12_ARATH » Protein SCO1 homolog 2, mitochondrial
MLPCRRLVLS CKNQAASFLR RCGPSKRIQS VNYCKSTRQG HEIPDVKPLF PTGGGTQAPS RSRARYAVPA ILLGFAGFVG FLHYNDERRA VPRGQASSNS GCGCGSNTTV KGPIIGGPFT LVSTENKIVT ENDFCGKWVL LYFGYSFSPD VGPEQLKMMS KAVDKLESKH NEKILPVFVT LDPQRDTPSH LHAYLKEFDS RILGLTGTAS AMRQMAQEYR VYFKKVQEDG EDYLVDTSHN MYLINPKMEI VRCFGVEYNP DELSQELLKE VASVSQ