SC6B2_YEAST » Protein transport protein SBH2

SC6B2_YEAST » Protein transport protein SBH2
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
SC6B2_YEAST » Protein transport protein SBH2 » Ssh1 complex subunit SBH2;Ssh1 complex subunit beta;
Hydrophobic Thickness 34.4 ± 3.4 Å
Tilt Angle 18 ± 2°
ΔGtransfer -26.2 kcal/mol
ΔGfold -17.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 61-85 (59-87)
Pathways

Phagosome (KEGG)

Protein export (KEGG)

Protein processing in endoplasmic reticulum (KEGG)

Sphingolipid metabolism (KEGG)

PDB 2ww9 (1-87), 2wwa (1-87)
OPM 2ww9, 2wwa
Complexes none
Interactions

HLJ1, Complex: SC6B2:HLJ1

MGA2, Complex: SC6B2:MGA2

NEM1, Complex: SC6B2:NEM1

OST1, Complex: OST1:SC6B2, PubMed

OST4, Complex: OST4:SC6B2, PubMed

OSTB, Complex: OSTB:SC6B2, PubMed

SC61G, Complex: SSH1:SC61G:SC61A:SC6B2:SEC62, PubMed

SC6B1, Complex: SC6B1:SC6B2

SEC22, Complex: SC6B2:SEC22

SRPB, Complex: SRPB:SC6B2

UBX2, Complex: SC6B2:UBX2

Domains

AA: 42-82, PDBID: 2WW9, Subunit C, Seq Identity:100%, Sec61beta family

UniProt annotation for SC6B2_YEAST » Protein transport protein SBH2
FUNCTION: Part of the Ssh1 complex, which probably is the major component of a channel-forming translocon complex that may function exclusively in the cotranslational pathway of protein endoplasmic reticulum (ER) import.

SUBUNIT: Component of the heterotrimeric Ssh1 complex, which is composed of SSH1, SBH2 and SSS1.

MISCELLANEOUS: Present with 414 molecules/cell in log phase SD medium.

UniProt features for SC6B2_YEAST » Protein transport protein SBH2
CHAIN 1 88 Protein transport protein SBH2.
Amino Acid Sequence for SC6B2_YEAST » Protein transport protein SBH2
MAASVPPGGQ RILQKRRQAQ SIKEKQAKQT PTSTRQAGYG GSSSSILKLY TDEANGFRVD SLVVLFLSVG FIFSVIALHL LTKFTHII