SC61G_HUMAN » Protein transport protein Sec61 subunit gamma

SC61G_HUMAN » Protein transport protein Sec61 subunit gamma
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
SC61G_HUMAN » Protein transport protein Sec61 subunit gamma »
Hydrophobic Thickness 31.6 ± 7.0 Å
Tilt Angle 38 ± 5°
ΔGtransfer -21.9 kcal/mol
ΔGfold -16.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 32-57 (32-59)
Pathways

Gene Expression (Reactome)

Immune System (Reactome)

Phagosome (KEGG)

Protein export (KEGG)

Protein processing in endoplasmic reticulum (KEGG)

Vibrio cholerae infection (KEGG)

PDB none
OPM 2wwb (CANFA), 4cg5 (CANFA), 4cg6 (CANFA), 4cg7 (CANFA)
Complexes

S61A1:SC61G:SC61B_CANFA

Interactions

CREB3, Complex: SC61G:CREB3

SC61B, Complex: S61A2:SC61G:S61A1:SC61B, PubMed

SC61B, Complex: SC61G:S61A1:SC61B, PDBID: 4cg5, PubMed

Domains

AA: 12-65, PDBID: 2WWB, Subunit B, Seq Identity:100%, SecE/Sec61-gamma subunits of protein translocation complex

UniProt annotation for SC61G_HUMAN » Protein transport protein Sec61 subunit gamma
FUNCTION: Necessary for protein translocation in the endoplasmic reticulum.

SUBUNIT: Heterotrimeric complex composed of SEC61-alpha, SEC61- beta and SEC61-gamma.

UniProt features for SC61G_HUMAN » Protein transport protein Sec61 subunit gamma
CHAIN 1 68 Protein transport protein Sec61 subunit gamma.
Amino Acid Sequence for SC61G_HUMAN » Protein transport protein Sec61 subunit gamma
MDQVMQFVEP SRQFVKDSIR LVKRCTKPDR KEFQKIAMAT AIGFAIMGFI GFFVKLIHIP INNIIVGG