SBIR1_ARATH » Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1

SBIR1_ARATH » Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SBIR1_ARATH » Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 » Protein EVERSHED;Protein SUPPRESSOR OF BIR1-1;
Hydrophobic Thickness 40.4 ± 1.8 Å
Tilt Angle 4 ± 2°
ΔGtransfer -58.8 kcal/mol
ΔGfold -15.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 284-316 (279-316)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: SBIR1:BETL2

PAM74, Complex: SBIR1:PAM74

UBC34, Complex: SBIR1:UBC34

WAK3, Complex: SBIR1:WAK3

Domains

AA: 111-171, PDBID: 2ID5, Subunit D, Seq Identity:39%, Leucine rich repeat

AA: 347-637, PDBID: 3DTC, Subunit A, Seq Identity:27%, Protein kinase domain

UniProt annotation for SBIR1_ARATH » Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1
FUNCTION: Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Promotes the activation of plant defense and cell death. Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

TISSUE SPECIFICITY: Mostly present in leaves and flowers, with increasing expression in older flowers.

DEVELOPMENTAL STAGE: Expressed in floral organ abscission zones (AZs) prior to cell separation and subsequent shedding. Also present within the style of developing fruits, at the bases of cauline leaves, and in the stems of the first rosette leaves.

UniProt features for SBIR1_ARATH » Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1
SIGNAL 1 31 Potential.
CHAIN 32 641 Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1.
REPEAT 112 133 LRR 1.
REPEAT 136 159 LRR 2.
REPEAT 160 182 LRR 3.
REPEAT 183 205 LRR 4.
REPEAT 207 228 LRR 5.
DOMAIN 347 641 Protein kinase.
ACT_SITE 489 489 Proton acceptor (By similarity).
Amino Acid Sequence for SBIR1_ARATH » Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1
MAVPTGSANL FLRPLILAVL SFLLLSSFVS SVEWLDIDSS DLKALQVIET ELGVNSQRSS ASDVNPCGRR GVFCERRHSA TTGEYVLRVT RLVYRSRSLT GTISPVIGML SELKELTLSN NQLVNAVPVD ILSCKQLEVL DLRKNRFSGQ IPGNFSSLSR LRILDLSSNK LSGNLNFLKN LRNLENLSVA NNLFSGKIPE QIVSFHNLRF FDFSGNRYLE GPAPVMSSIK LQTSPHQTRH ILAETPTSSP TNKPNNSTTS KAPKGAPKPG KLKKKKKKSK KKKVAAWILG FVVGAIGGTI SGFVFSVLFK LIIQAIRGSE KPPGPSIFSP LIKKAEDLAF LENEEALASL EIIGRGGCGE VFKAELPGSN GKIIAVKKVI QPPKDADELT DEDSKFLNKK MRQIRSEINT VGHIRHRNLL PLLAHVSRPE CHYLVYEYME KGSLQDILTD VQAGNQELMW PARHKIALGI AAGLEYLHMD HNPRIIHRDL KPANVLLDDD MEARISDFGL AKAMPDAVTH ITTSHVAGTV GYIAPEFYQT HKFTDKCDIY SFGVILGILV IGKLPSDEFF QHTDEMSLIK WMRNIITSEN PSLAIDPKLM DQGFDEQMLL VLKIACYCTL DDPKQRPNSK DVRTMLSQIK H