RRBP1_HUMAN » Ribosome-binding protein 1

RRBP1_HUMAN » Ribosome-binding protein 1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
RRBP1_HUMAN » Ribosome-binding protein 1 » 180 kDa ribosome receptor homolog;RRp; ES/130-related protein;Ribosome receptor protein;
Hydrophobic Thickness 36.8 ± 2.6 Å
Tilt Angle 0 ± 1°
ΔGtransfer -49.0 kcal/mol
ΔGfold -17.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 3-31 (3-34)
Pathways

Protein processing in endoplasmic reticulum (KEGG)

PDB none
OPM none
Complexes none
Interactions

SRPRB, Complex: RRBP1:SRPRB, PubMed

Domains

AA: 33-171, Ribosome receptor lysine/proline rich region

UniProt annotation for RRBP1_HUMAN » Ribosome-binding protein 1
FUNCTION: Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.
UniProt features for RRBP1_HUMAN » Ribosome-binding protein 1
CHAIN 1 1410 Ribosome-binding protein 1.
REPEAT 197 206 1.
REPEAT 207 216 2.
REPEAT 217 226 3.
REPEAT 227 236 4.
REPEAT 237 246 5.
REPEAT 247 256 6.
REPEAT 257 266 7.
REPEAT 267 276 8.
REPEAT 277 286 9.
REPEAT 287 296 10.
REPEAT 297 306 11.
REPEAT 307 316 12.
REPEAT 317 326 13.
REPEAT 327 336 14.
REPEAT 337 346 15.
REPEAT 347 356 16.
REPEAT 357 366 17.
REPEAT 367 376 18.
REPEAT 377 386 19.
REPEAT 387 396 20.
REPEAT 397 406 21.
REPEAT 407 416 22.
REPEAT 417 426 23.
REPEAT 427 436 24.
REPEAT 437 446 25.
REPEAT 447 456 26.
REPEAT 457 466 27.
REPEAT 467 476 28.
REPEAT 477 486 29.
REPEAT 487 496 30.
REPEAT 497 506 31.
REPEAT 507 516 32.
REPEAT 517 526 33.
REPEAT 527 534 34; approximate.
REPEAT 535 544 35.
REPEAT 545 554 36; approximate.
REPEAT 555 564 37.
REPEAT 565 574 38.
REPEAT 575 584 39; approximate.
REPEAT 585 594 40.
REPEAT 595 604 41.
REGION 197 604 41 X 10 AA approximate tandem repeats of [TN]-Q-[GSA]-[KRQT]-K-[ATGSV]-[ED]- [GTAS]-[ATIS]-[PQTAS].
Amino Acid Sequence for RRBP1_HUMAN » Ribosome-binding protein 1
MDIYDTQTLG VVVFGGFMVV SAIGIFLVST FSMKETSYEE ALANQRKEMA KTHHQKVEKK KKEKTVEKKG KTKKKEEKPN GKIPDHDPAP NVTVLLREPV RAPAVAVAPT PVQPPIIVAP VATVPAMPQE KLASSPKDKK KKEKKVAKVE PAVSSVVNSI QVLTSKAAIL ETAPKEVPMV VVPPVGAKGN TPATGTTQGK KAEGTQNQSK KAEGAPNQGR KAEGTPNQGK KTEGTPNQGK KAEGTPNQGK KAEGTPNQGK KAEGAQNQGK KVDTTPNQGK KVEGAPTQGR KAEGAQNQAK KVEGAQNQGK KAEGAQNQGK KGEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KSEGAQNQGK KVEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KVEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGQ KGEGAQNQGK KTEGAQGKKA ERSPNQGKKG EGAPIQGKKA DSVANQGTKV EGITNQGKKA EGSPSEGKKA EGSPNQGKKA DAAANQGKKT ESASVQGRNT DVAQSPEAPK QEAPAKKKSG SKKKGEPGPP DADGPLYLPY KTLVSTVGSM VFNEGEAQRL IEILSEKAGI IQDTWHKATQ KGDPVAILKR QLEEKEKLLA TEQEDAAVAK SKLRELNKEM AAEKAKAAAG EAKVKKQLVA REQEITAVQA RMQASYREHV KEVQQLQGKI RTLQEQLENG PNTQLARLQQ ENSILRDALN QATSQVESKQ NAELAKLRQE LSKVSKELVE KSEAVRQDEQ QRKALEAKAA AFEKQVLQLQ ASHRESEEAL QKRLDEVSRE LCHTQSSHAS LRADAEKAQE QQQQMAELHS KLQSSEAEVR SKCEELSGLH GQLQEARAEN SQLTERIRSI EALLEAGQAR DAQDVQASQA EADQQQTRLK ELESQVSGLE KEAIELREAV EQQKVKNNDL REKNWKAMEA LATAEQACKE KLLSLTQAKE ESEKQLCLIE AQTMEALLAL LPELSVLAQQ NYTEWLQDLK EKGPTLLKHP PAPAEPSSDL ASKLREAEET QSTLQAECDQ YRSILAETEG MLRDLQKSVE EEEQVWRAKV GAAEEELQKS RVTVKHLEEI VEKLKGELES SDQVREHTSH LEAELEKHMA AASAECQNYA KEVAGLRQLL LESQSQLDAA KSEAQKQSDE LALVRQQLSE MKSHVEDGDI AGAPASSPEA PPAEQDPVQL KTQLEWTEAI LEDEQTQRQK LTAEFEEAQT SACRLQEELE KLRTAGPLES SETEEASQLK ERLEKEKKLT SDLGRAATRL QELLKTTQEQ LAREKDTVKK LQEQLEKAED GSSSKEGTSV