RPK1_ARATH » Probable LRR receptor-like serine/threonine-protein kinase RPK1

RPK1_ARATH » Probable LRR receptor-like serine/threonine-protein kinase RPK1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
RPK1_ARATH » Probable LRR receptor-like serine/threonine-protein kinase RPK1 » Protein TOADSTOOL 1;Receptor-like protein kinase 1;
Hydrophobic Thickness 37.2 ± 5.8 Å
Tilt Angle 27 ± 1°
ΔGtransfer -30.3 kcal/mol
ΔGfold -26.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 196-222 (196-226)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 30-70, PDBID: 4J0M, Subunit B, Seq Identity:44%, Leucine rich repeat N-terminal domain

AA: 261-531, PDBID: 3TL8, Subunit A, Seq Identity:42%, Protein kinase domain

UniProt annotation for RPK1_ARATH » Probable LRR receptor-like serine/threonine-protein kinase RPK1
FUNCTION: Involved in the main abscisic acid-mediated (ABA) signaling pathway and in early ABA perception. Together with RPK2, required for pattern formation along the radial axis (e.g. the apical embryonic domain cell types that generate cotyledon primordia), and the apical-basal axis (e.g. differentiation of the basal pole during early embryogenesis).

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Expressed in roots, stems, leaves, and flowers.

DEVELOPMENTAL STAGE: First detected in the suspensor cells of octant-stage embryos, in the basal plasma membrane of the basal- most cell of the suspensor, which is in direct contact with maternal tissue. Expressed in the central domain protodermal cells when cotyledon primordia become recognizable. Later observed throughout the central domain and basal domain of the embryo proper, as well as the suspensor.

INDUCTION: By ABA (at protein level), dehydration, high salt levels, and low temperature.

UniProt features for RPK1_ARATH » Probable LRR receptor-like serine/threonine-protein kinase RPK1
SIGNAL 1 19 Potential.
CHAIN 20 540 Probable LRR receptor-like serine/threonine-protein kinase RPK1.
REPEAT 118 142 LRR 1.
REPEAT 144 169 LRR 2.
DOMAIN 261 535 Protein kinase.
ACT_SITE 385 385 Proton acceptor (By similarity).
Amino Acid Sequence for RPK1_ARATH » Probable LRR receptor-like serine/threonine-protein kinase RPK1
MKLLGLVFLL FNLFMFSFSR KLLTESGGGL HDEAALLKLK SSFLDPNGVL SSWVSDSSSN HCSWYGVSCN SDSRVVSLIL RGCDELEGSG VLHLPDLSSC SSSKRRLGGV ISPVVGDLSE IRVLSLSFND LRGEIPKEIW GLEKLEILDL KGNNFIGGIR VVDNVVLRKL MSFEDEDEIG PSSADDDSPG KSGLYPIEIA SIVSASVIVF VLLVLVILFI YTRKWKRNSQ VQVDEIKEIK VFVDIGIPLT YEIIVRATGY FSNSNCIGHG GFGSTYKAEV SPTNVFAVKR LSVGRFQGDQ QFHAEISALE MVRHPNLVML IGYHASETEM FLIYNYLSGG NLQDFIKERS KAAIEWKVLH KIALDVARAL SYLHEQCSPK VLHRDIKPSN ILLDNNYNAY LSDFGLSKLL GTSQSHVTTG VAGTFGYVAP EYAMTCRVSE KADVYSYGIV LLELISDKRA LDPSFSSHEN GFNIVSWAHM MLSQGKAKEV FTTGLWETGP PDDLVEVLHL ALKCTVDSLS IRPTMKQAVR LLKRIQPSRL