QMCA_ECOLI » Protein QmcA

QMCA_ECOLI » Protein QmcA
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Topology in Bacterial Gram-negative inner membrane
Topologyextracellular side
cytoplasmic side
QMCA_ECOLI » Protein QmcA »
Hydrophobic Thickness 34.6 ± 3.0 Å
Tilt Angle 30 ± 2°
ΔGtransfer -27.7 kcal/mol
ΔGfold -13.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 2-23 (1-23)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 21-204, PDBID: 4FVF, Subunit A, Seq Identity:35%, SPFH domain / Band 7 family

AA: 237-300, C-terminal region of band_7

UniProt annotation for QMCA_ECOLI » Protein QmcA
FUNCTION: Identified as a multi-copy suppressor of an FtsH/HtpX protease double disruption mutant. May play a role in the quality control of integral membrane proteins.

SUBUNIT: Forms oligomers. Probably interacts weakly with FtsH.

UniProt features for QMCA_ECOLI » Protein QmcA
CHAIN 1 305 Protein QmcA.
Amino Acid Sequence for QMCA_ECOLI » Protein QmcA
MLIFIPILIF VALVIVGAGV KIVPQGYQWT VERFGRYTKT LQPGLSLVVP FMDRIGRKIN MMEQVLDIPS QEVISKDNAN VTIDAVCFIQ VIDAPRAAYE VSNLELAIIN LTMTNIRTVL GSMELDEMLS QRDSINSRLL RIVDEATNPW GIKVTRIEIR DVRPPAELIS SMNAQMKAER TKRAYILEAE GIRQAEILKA EGEKQSQILK AEGERQSAFL QAEARERSAE AEARATKMVS EAIASGDIQA VNYFVAQKYT EALQQIGSSS NSKVVMMPLE ASSLMGSIAG IAELVKDSAN KRTQP