PXL1_ARATH » Leucine-rich repeat receptor-like protein kinase PXL1

PXL1_ARATH » Leucine-rich repeat receptor-like protein kinase PXL1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PXL1_ARATH » Leucine-rich repeat receptor-like protein kinase PXL1 » Protein PHLOEM INTERCALATED WITH XYLEM-LIKE 1;
Hydrophobic Thickness 36.0 ± 1.6 Å
Tilt Angle 2 ± 2°
ΔGtransfer -49.3 kcal/mol
ΔGfold -12.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 645-670 (637-673)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: PXL1:BETL2

MSBP2, Complex: PXL1:MSBP2

UBC34, Complex: PXL1:UBC34

Domains

AA: 27-74, PDBID: 4MN8, Subunit A, Seq Identity:38%, Leucine rich repeat N-terminal domain

AA: 245-305, PDBID: 4M7E, Subunit C, Seq Identity:44%, Leucine rich repeat

AA: 317-377, PDBID: 4J0M, Subunit A, Seq Identity:48%, Leucine rich repeat

AA: 532-592, PDBID: 4MN8, Subunit A, Seq Identity:46%, Leucine rich repeat

AA: 714-999, PDBID: 1U5Q, Subunit A, Seq Identity:29%, Protein kinase domain

UniProt annotation for PXL1_ARATH » Leucine-rich repeat receptor-like protein kinase PXL1
FUNCTION: Involved in the regulation of procambium maintenance and polarity during vascular-tissue development.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

UniProt features for PXL1_ARATH » Leucine-rich repeat receptor-like protein kinase PXL1
SIGNAL 1 23 Potential.
CHAIN 24 1029 Leucine-rich repeat receptor-like protein kinase PXL1.
REPEAT 81 100 LRR 1.
REPEAT 101 124 LRR 2.
REPEAT 126 148 LRR 3.
REPEAT 149 172 LRR 4.
REPEAT 174 195 LRR 5.
REPEAT 196 222 LRR 6.
REPEAT 224 243 LRR 7.
REPEAT 244 268 LRR 8.
REPEAT 269 292 LRR 9.
REPEAT 293 316 LRR 10.
REPEAT 317 339 LRR 11.
REPEAT 341 364 LRR 12.
REPEAT 365 388 LRR 13.
REPEAT 389 412 LRR 14.
REPEAT 414 436 LRR 15.
REPEAT 437 461 LRR 16.
REPEAT 463 483 LRR 17.
REPEAT 485 507 LRR 18.
REPEAT 508 531 LRR 19.
REPEAT 532 555 LRR 20.
REPEAT 556 579 LRR 21.
REPEAT 581 604 LRR 22.
DOMAIN 714 1007 Protein kinase.
ACT_SITE 854 854 Proton acceptor (By similarity).
Amino Acid Sequence for PXL1_ARATH » Leucine-rich repeat receptor-like protein kinase PXL1
MAIPRLFFLF YYIGFALFPF VSSETFQNSE QEILLAFKSD LFDPSNNLQD WKRPENATTF SELVHCHWTG VHCDANGYVA KLLLSNMNLS GNVSDQIQSF PSLQALDLSN NAFESSLPKS LSNLTSLKVI DVSVNSFFGT FPYGLGMATG LTHVNASSNN FSGFLPEDLG NATTLEVLDF RGGYFEGSVP SSFKNLKNLK FLGLSGNNFG GKVPKVIGEL SSLETIILGY NGFMGEIPEE FGKLTRLQYL DLAVGNLTGQ IPSSLGQLKQ LTTVYLYQNR LTGKLPRELG GMTSLVFLDL SDNQITGEIP MEVGELKNLQ LLNLMRNQLT GIIPSKIAEL PNLEVLELWQ NSLMGSLPVH LGKNSPLKWL DVSSNKLSGD IPSGLCYSRN LTKLILFNNS FSGQIPEEIF SCPTLVRVRI QKNHISGSIP AGSGDLPMLQ HLELAKNNLT GKIPDDIALS TSLSFIDISF NHLSSLSSSI FSSPNLQTFI ASHNNFAGKI PNQIQDRPSL SVLDLSFNHF SGGIPERIAS FEKLVSLNLK SNQLVGEIPK ALAGMHMLAV LDLSNNSLTG NIPADLGASP TLEMLNVSFN KLDGPIPSNM LFAAIDPKDL VGNNGLCGGV LPPCSKSLAL SAKGRNPGRI HVNHAVFGFI VGTSVIVAMG MMFLAGRWIY TRWDLYSNFA REYIFCKKPR EEWPWRLVAF QRLCFTAGDI LSHIKESNII GMGAIGIVYK AEVMRRPLLT VAVKKLWRSP SPQNDIEDHH QEEDEEDDIL REVNLLGGLR HRNIVKILGY VHNEREVMMV YEYMPNGNLG TALHSKDEKF LLRDWLSRYN VAVGVVQGLN YLHNDCYPPI IHRDIKSNNI LLDSNLEARI ADFGLAKMML HKNETVSMVA GSYGYIAPEY GYTLKIDEKS DIYSLGVVLL ELVTGKMPID PSFEDSIDVV EWIRRKVKKN ESLEEVIDAS IAGDCKHVIE EMLLALRIAL LCTAKLPKDR PSIRDVITML AEAKPRRKSV CQVAGDLPIF RNSPVVGLI