PRR7_HUMAN » Proline-rich protein 7

PRR7_HUMAN » Proline-rich protein 7
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PRR7_HUMAN » Proline-rich protein 7 » Synaptic proline-rich membrane protein;
Hydrophobic Thickness 33.6 ± 3.6 Å
Tilt Angle 37 ± 7°
ΔGtransfer -28.2 kcal/mol
ΔGfold -20.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 9-35 (7-44)
Pathways

Circadian rhythm - plant (KEGG)

PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 3-66, WW domain-binding protein 1

UniProt annotation for PRR7_HUMAN » Proline-rich protein 7
SUBUNIT: Found in a postsynaptic membrane complex with DLG4 and GRIN1. Interacts with DLG4. Interacts preferentially to the PDZ3 domain of DLG4 and to lesser degree to PDZ2 but not to the PDZ1 (By similarity).
UniProt features for PRR7_HUMAN » Proline-rich protein 7
CHAIN 1 274 Proline-rich protein 7.
MOTIF 272 274 PDZ-binding (Potential).
Amino Acid Sequence for PRR7_HUMAN » Proline-rich protein 7
MVMSQGTYTF LTCFAGFWLI WGLIVLLCCF CSFLRRRLKR RQEERLREQN LRALELEPLE LEGSLAGSPP GLAPPQPPPH RSRLEAPAHA HSHPHVHVHP LLHHGPAQPH AHAHPHPHHH ALPHPPPTHL SVPPRPWSYP RQAESDMSKP PCYEEAVLMA EPPPPYSEVL TDTRGLYRKI VTPFLSRRDS AEKQEQPPPS YKPLFLDRGY TSALHLPSAP RPAPPCPALC LQADRGRRVF PSWTDSELSS REPLEHGAWR LPVSIPLFGR TTAV