PPR3F_HUMAN » Protein phosphatase 1 regulatory subunit 3F

PPR3F_HUMAN » Protein phosphatase 1 regulatory subunit 3F
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PPR3F_HUMAN » Protein phosphatase 1 regulatory subunit 3F » R3F;
Hydrophobic Thickness 30.8 ± 5.8 Å
Tilt Angle 59 ± 0°
ΔGtransfer -27.3 kcal/mol
ΔGfold -11.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 762-795 (762-798)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 150-284, PDBID: 2M83, Subunit A, Seq Identity:28%, Carbohydrate/starch-binding module (family 21)

UniProt annotation for PPR3F_HUMAN » Protein phosphatase 1 regulatory subunit 3F
FUNCTION: Glycogen-targeting subunit for protein phosphatase 1 (PP1).

TISSUE SPECIFICITY: Expressed in brain, skeletal muscle and heart.

UniProt features for PPR3F_HUMAN » Protein phosphatase 1 regulatory subunit 3F
CHAIN 1 799 Protein phosphatase 1 regulatory subunit 3F.
DOMAIN 128 284 CBM21.
MOTIF 36 39 PP1-binding motif.
Amino Acid Sequence for PPR3F_HUMAN » Protein phosphatase 1 regulatory subunit 3F
MARTAPVEPP LRHSAPPSPA AGEPRTSVEA AVAPRRVLFA DEALGLPLAQ LRRYRPWGGP GAGKMAAAAG QDGGGGGGAD EDDDGEDGDE GEEEEEACPE PSPLCPVPAG GGFYLVPTFS LPPAPGRLER LGRVMVELEA LLPPPGAVPG GAGVWVPGGR PPVLRGLVRV LNRSFEKAVH VRASHDGWAS FCDHPARYVP RSPPWAGAGG TGAGDPILDP GLGLGPGQAS ASSPDDGGRT DRFAFQLPFA EGAGDGARLD FVVRYETPEG TFWANNHGRN YTVLLRIAPA PTPTDAEGLP QQQQLPQLEP QPECQGPVEA EARQLKSCMK PVRRRPAEEE LKTKNMDDNT FAMAEHPDVQ ESVGPLVAPT PLRPWPQMTL QVSDVPMTGN PAEEGDVPRS SPPVAFTEVL QAPAIRIPPS SPLCGLGGSP RDQASGPDAS EGATGPFLEP SQQQAEATWG VSSENGGGLE AVSGSEELLG EDTIDQELEQ LYLSHLSRLR AAVAAGGAGG GGEGSTDGGM SPSHPLGILT DRDLILKWPG PERALNSALA EEITLHYARL GRGVELIKDT EDPDDEGEGE EGLSVTPSSP EGDSPKESPP EILSGARSVV ATMGDVWLPW AEGSGCDGPV VLGTEGQFIG DPEKGMGKDT SSLHMNRVIA GVTESLGEAG TEAQIEVTSE WAGSLDPISG KEPASPVLLQ GQNPTLLSPL GAEVCLSSVA RPHVSSQDEK DAGPSLEPPK KSPTLAVPAE CVCALPPQLR GPLTQTLGVL AGLVVVPVAL NSGVSLLVLA LCLSLAWFS