PHB2_DICDI » Prohibitin-2

PHB2_DICDI » Prohibitin-2
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
PHB2_DICDI » Prohibitin-2 »
Hydrophobic Thickness 30.0 ± 3.2 Å
Tilt Angle 1 ± 0°
ΔGtransfer -16.6 kcal/mol
ΔGfold -6.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 21-41 (20-42)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 42-223, PDBID: 4FVF, Subunit A, Seq Identity:19%, SPFH domain / Band 7 family

UniProt annotation for PHB2_DICDI » Prohibitin-2
FUNCTION: Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.
UniProt features for PHB2_DICDI » Prohibitin-2
CHAIN 1 293 Prohibitin-2.
COILED 190 235 Potential.
Amino Acid Sequence for PHB2_DICDI » Prohibitin-2
MNNKKFQVNF NNIPKLPKGS FGGGFGLLAL GGVGLLALSS LVNVEGGHRA IVFNRFVGIK NKVYNEGTHF IVPWFERAEI YDVRAKPRSI SSLTGSKDLQ MVNITIRVLS KPKVSQLPAI YRTLGKDYDE RVLPSIVNEI LKSIVAQFNA SQLITQREQV SRLIFKRLVD RAKDFNIELD DVSITHLNFG REYAAAIEAK QVAQQEAERA RFLVEKALQD KRSIIVKAEG EAQSAQLIND AIKQSPYLVQ LRTLEASKEI AHILSKSPNK LYISNETLLL NGFDLNNNQQ PKK