PHB2_ARATH » Prohibitin-2, mitochondrial

PHB2_ARATH » Prohibitin-2, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
PHB2_ARATH » Prohibitin-2, mitochondrial » Atphb2;
Hydrophobic Thickness 28.4 ± 3.8 Å
Tilt Angle 9 ± 10°
ΔGtransfer -12.9 kcal/mol
ΔGfold -2.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 14-32 (14-37)
Pathways none
PDB none
OPM none
Complexes none
Interactions

FTSHA, Complex: PHB2:FTSHA

PHB1, Complex: PHB1:PHB2, PubMed

Domains

AA: 37-227, PDBID: 4FVF, Subunit A, Seq Identity:17%, SPFH domain / Band 7 family

UniProt annotation for PHB2_ARATH » Prohibitin-2, mitochondrial
FUNCTION: Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.

SUBUNIT: Component of a prohibitin multimeric complex in mitochondrial membranes.

TISSUE SPECIFICITY: Mostly expressed in proliferative tissues, including vasculature, shoot and root apical tissues.

UniProt features for PHB2_ARATH » Prohibitin-2, mitochondrial
CHAIN 1 286 Prohibitin-2, mitochondrial.
COILED 186 219 Potential.
Amino Acid Sequence for PHB2_ARATH » Prohibitin-2, mitochondrial
MSFNKVPNIP GAPALSALLK VSVIGGLGVY ALTNSLYNVD GGHRAVMFNR LTGIKEKVYP EGTHFMVPWF ERPIIYDVRA RPYLVESTTG SHDLQMVKIG LRVLTRPMGD RLPQIYRTLG ENYSERVLPS IIHETLKAVV AQYNASQLIT QREAVSREIR KILTERASNF DIALDDVSIT TLTFGKEFTA AIEAKQVAAQ EAERAKFIVE KAEQDRRSAV IRAQGEAKSA QLIGQAIANN QAFITLRKIE AAREIAQTIA QSANKVYLSS NDLLLNLQEM NLEPKK