PHB1_ARATH » Prohibitin-1, mitochondrial

PHB1_ARATH » Prohibitin-1, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
PHB1_ARATH » Prohibitin-1, mitochondrial » Atphb1;
Hydrophobic Thickness 28.0 ± 4.0 Å
Tilt Angle 10 ± 7°
ΔGtransfer -11.7 kcal/mol
ΔGfold -1.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 14-32 (14-37)
Pathways none
PDB none
OPM none
Complexes none
Interactions

FTSHA, Complex: PHB1:FTSHA

PHB2, Complex: PHB1:PHB2, PubMed

PHB3, Complex: PHB1:PHB3, PubMed

PHB6, Complex: PHB1:PHB6, PubMed

Domains

AA: 37-227, PDBID: 4FVF, Subunit A, Seq Identity:16%, SPFH domain / Band 7 family

UniProt annotation for PHB1_ARATH » Prohibitin-1, mitochondrial
FUNCTION: Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.

SUBUNIT: Component of a prohibitin multimeric complex in mitochondrial membranes.

TISSUE SPECIFICITY: Mostly expressed in proliferative tissues, including vasculature, shoot and root apical tissues.

UniProt features for PHB1_ARATH » Prohibitin-1, mitochondrial
CHAIN 1 288 Prohibitin-1, mitochondrial.
COILED 186 219 Potential.
Amino Acid Sequence for PHB1_ARATH » Prohibitin-1, mitochondrial
MNNVKVPKIP GGGAISTLLK VGIIGGLGLY GATHSLYNVE GGHRAIMFNR LVGIKDKVYP EGTHLMIPWF ERPVIYDVRA RPYLVESTSG SRDLQMVKIG LRVLTRPMAD QLPEIYRSLG ENYSERVLPS IINETLKAVV AQYNASQLIT QREAVSREIR KILTERAANF NVALDDVSIT NLTFGKEFTA AIEAKQVAAQ EAERAKFIVE KAEQDKRSAV IRAQGEAKSA QLIGQAIANN QAFITLRKIE AAREIAQTIA NSANKVYLSS DDLLLNLQGM NLDVDAKN