PEX14_YEAST » Peroxisomal membrane protein PEX14

PEX14_YEAST » Peroxisomal membrane protein PEX14
Magnify PEX14_YEAST » Peroxisomal membrane protein PEX14Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Peroxisome membrane
Topologyperoxisome lumenal side
cytoplasmic side
PEX14_YEAST » Peroxisomal membrane protein PEX14 » Peroxin-14;
Hydrophobic Thickness 30.8 ± 3.1 Å
Tilt Angle 11 ± 9°
ΔGtransfer -14.9 kcal/mol
ΔGfold -6.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 94-115 (91-118)
Pathways none
PDB 2v1r (P/Q/R=83-96), 1n5z (P/Q=83-96)
OPM none
Complexes none
Interactions none
Domains

AA: 9-123, PDBID: 2W84, Subunit A, Seq Identity:39%, Peroxisomal membrane anchor protein (Pex14p) conserved region

UniProt annotation for PEX14_YEAST » Peroxisomal membrane protein PEX14
FUNCTION: Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17.
UniProt features for PEX14_YEAST » Peroxisomal membrane protein PEX14
CHAIN 2 341 Peroxisomal membrane protein PEX14.

MOTIF 86 94 SH3-binding.

Amino Acid Sequence for PEX14_YEAST » Peroxisomal membrane protein PEX14
MSDVVSKDRK ALFDSAVSFL KDESIKDAPL LKKIEFLKSK GLTEKEIEIA MKEPKKDGIV GDEVSKKIGS TENRASQDMY LYEAMPPTLP HRDWKDYFVM ATATAGLLYG AYEVTRRYVI PNILPEAKSK LEGDKKEIDD QFSKIDTVLN AIEAEQAEFR KKESETLKEL SDTIAELKQA LVQTTRSREK IEDEFRIVKL EVVNMQNTID KFVSDNDGMQ ELNNIQKEME SLKSLMNNRM ESGNAQDNRL FSISPNGIPG IDTIPSASEI LAKMGMQEES DKEKENGSDA NKDDNAVPAW KKAREQTIDS NASIPEWQKN TAANEISVPD WQNGQVEDSI P