PEX14_ARATH » Peroxisomal membrane protein PEX14

PEX14_ARATH » Peroxisomal membrane protein PEX14
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Topology in Peroxisome membrane
Topologyperoxisome lumenal side
cytoplasmic side
PEX14_ARATH » Peroxisomal membrane protein PEX14 » Peroxin-14;AtPEX14; Peroxisome biogenesis protein 14;Pex14p;Protein PEROXISOME DEFECTIVE 2;
Hydrophobic Thickness 30.8 ± 4.4 Å
Tilt Angle 17 ± 12°
ΔGtransfer -11.1 kcal/mol
ΔGfold -11.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 152-173 (148-175)
Pathways

Peroxisome (KEGG)

PDB none
OPM none
Complexes

PEX14:PEX13_YEAST

Interactions none
Domains

AA: 54-181, PDBID: 2W84, Subunit A, Seq Identity:39%, Peroxisomal membrane anchor protein (Pex14p) conserved region

UniProt annotation for PEX14_ARATH » Peroxisomal membrane protein PEX14
FUNCTION: Controls intracellular transport of both PTS1- and PTS2- containing proteins. Required for the proper targeting of PEX7 to the peroxisome.

SUBUNIT: Interacts with PEX5 (via the WXXXF/Y repeats), but not with PEX7 and PTS1-containing proteins.

TISSUE SPECIFICITY: Expressed in flowers, siliques, leaves and roots.

DEVELOPMENTAL STAGE: Expressed at the early stage of germination and during the conversion of glyoxysomes to peroxisomes.

INDUCTION: By wounding and hydrogen peroxide, but not by jasmonate.

UniProt features for PEX14_ARATH » Peroxisomal membrane protein PEX14
CHAIN 1 507 Peroxisomal membrane protein PEX14.
REGION 58 65 Involved in interaction with PEX5.
REGION 78 97 Involved in interaction with PEX5.
Amino Acid Sequence for PEX14_ARATH » Peroxisomal membrane protein PEX14
MATHQQTQPP SDFPALADEN SQIPEATKPA NEVQQATIAQ DPPTSVFKNS EPIREDQIQN AIKFLSHPRV RGSPVIHRRS FLERKGLTKE EIDEAFRRVP DPPPSSQTTV TTSQDGQQAV STVQPQAMQP VVAAPAPLIV TPQAAFLSRF RWYHAILAVG VLAASGAGTA VFIKRSLIPR FKSWVQRIML EEETDPLKKA DAKPSLAEEA VAAAKAASAA ASDVARVSQE MMITKNEERK YFEDLTHLLG VQVQEMKSLS NNIRKLEGQS NNIPKIYSAD QEVYNGSVTT ARKPYTNGSN VDYDTRSARS ASPPAAPADS SAPPHPKSYM DIMSMIQRGE KPSNIREIND MPPNPNQPLS DPRIAPKSKP WDYGQAPQDE SSNGQWWQQK NPRSTDFGYE TTTAARFTAN QNETSTMEPA AFQRQRSWVP PQPPPVAMAE AVEAIRRPKP QAKIDQEAAA SDGQSGVSDE LQKITKFSES GGDGSGGIKI AEIQEETEQQ HISQEGN