PEX12_DICDI » Peroxisome assembly protein 12

PEX12_DICDI » Peroxisome assembly protein 12
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Topology in Peroxisome membrane
Topologyperoxisome lumenal side
cytoplasmic side
PEX12_DICDI » Peroxisome assembly protein 12 » Peroxin-12;
Hydrophobic Thickness 30.4 ± 2.4 Å
Tilt Angle 38 ± 3°
ΔGtransfer -23.4 kcal/mol
ΔGfold -9.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 258-284 (253-289)
Pathways

Peroxisome (KEGG)

PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 23-373, Pex2 / Pex12 amino terminal region

UniProt annotation for PEX12_DICDI » Peroxisome assembly protein 12
FUNCTION: Required for protein import into peroxisomes.
UniProt features for PEX12_DICDI » Peroxisome assembly protein 12
CHAIN 1 459 Putative peroxisome assembly protein 12.
ZN_FING 406 444 RING-type; degenerate.
COILED 196 232 Potential.
Amino Acid Sequence for PEX12_DICDI » Peroxisome assembly protein 12
MFMFNFDNGH DPNRPSFFEM LNQHQMMPSF KPALKYIFTV LSQRNPKFRY IVNYYDECFY SLLLLLEYHY LKYYEGSFSE NFYNLKRIKP RNNNANGDGD TLFSLLKRLV VTPSNAGQGP ETYTKSQILK KSFAMIRRNR AAASSSQQAK DDLNTMIQDS DRKESLIYLV LIPYFKGKLD EYYKKESDPL AELGLVSSDN NNNNNDNIND QIQQLEEQIQ QQQTIVNGNN NSNNNNKKLK IKFLILIRFL KGSKTLKKLK TIFLKVYPFI SAIYEALFFI YQLLYLYEYT NYYTPFFHFQ NIQLKRLNHK DIESHRVVIS NRRRDRINFV RDWPGSSFFV RLVSILDSIL DYSKYILPLS VFIFKSLEWW YSENRISAPT LPIPTPPTPS KRAPGGLEIP RDKRLCPLCL KERTNPTICG SGFVFCYPCI FGYVNEHSKC PITFLPTNTE QLRKIYETV