PERK8_ARATH » Proline-rich receptor-like protein kinase PERK8

PERK8_ARATH » Proline-rich receptor-like protein kinase PERK8
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PERK8_ARATH » Proline-rich receptor-like protein kinase PERK8 » Proline-rich extensin-like receptor kinase 8;AtPERK8;
Hydrophobic Thickness 37.6 ± 2.8 Å
Tilt Angle 0 ± 0°
ΔGtransfer -47.7 kcal/mol
ΔGfold -21.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 236-260 (235-265)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: PERK8:BETL2

CRK40, Complex: PERK8:CRK40

PAM74, Complex: PERK8:PAM74

WAK3, Complex: PERK8:WAK3

Domains

AA: 339-614, PDBID: 3TL8, Subunit A, Seq Identity:61%, Protein kinase domain

UniProt annotation for PERK8_ARATH » Proline-rich receptor-like protein kinase PERK8
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Mostly expressed in seedlings, roots, inflorescence bolts and flower buds.

UniProt features for PERK8_ARATH » Proline-rich receptor-like protein kinase PERK8
CHAIN 1 681 Proline-rich receptor-like protein kinase PERK8.
DOMAIN 339 617 Protein kinase.
ACT_SITE 463 463 Proton acceptor (By similarity).
Amino Acid Sequence for PERK8_ARATH » Proline-rich receptor-like protein kinase PERK8
MSLVPPLPIL SPPSSNSSTT APPPLQTQPT TPSAPPPVTP PPSPPQSPPP VVSSSPPPPV VSSPPPSSSP PPSPPVITSP PPTVASSPPP PVVIASPPPS TPATTPPAPP QTVSPPPPPD ASPSPPAPTT TNPPPKPSPS PPGETPSPPG ETPSPPKPSP STPTPTTTTS PPPPPATSAS PPSSNPTDPS TLAPPPTPLP VVPREKPIAK PTGPASNNGN NTLPSSSPGK SEVGTGGIVA IGVIVGLVFL SLFVMGVWFT RKRKRKDPGT FVGYTMPPSA YSSPQGSDVV LFNSRSSAPP KMRSHSGSDY MYASSDSGMV SNQRSWFSYD ELSQVTSGFS EKNLLGEGGF GCVYKGVLSD GREVAVKQLK IGGSQGEREF KAEVEIISRV HHRHLVTLVG YCISEQHRLL VYDYVPNNTL HYHLHAPGRP VMTWETRVRV AAGAARGIAY LHEDCHPRII HRDIKSSNIL LDNSFEALVA DFGLAKIAQE LDLNTHVSTR VMGTFGYMAP EYATSGKLSE KADVYSYGVI LLELITGRKP VDTSQPLGDE SLVEWARPLL GQAIENEEFD ELVDPRLGKN FIPGEMFRMV EAAAACVRHS AAKRPKMSQV VRALDTLEEA TDITNGMRPG QSQVFDSRQQ SAQIRMFQRM AFGSQDYSSD FFDRSQSHSS WGSRDQSRFV P