PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1

PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1
Magnify PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1 » Proline-rich extensin-like receptor kinase 1;AtPERK1;
Hydrophobic Thickness 38.8 ± 2.6 Å
Tilt Angle 0 ± 0°
ΔGtransfer -46.8 kcal/mol
ΔGfold -22.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 136-164 (132-168)
Pathways none
PDB none
OPM none
Complexes none
Interactions

PAM74, Complex: PERK1:PAM74

Y5830, Complex: Y5830:PERK1

Domains

AA: 280-553, PDBID: 2NRU, Subunit B, Seq Identity:42%, Protein tyrosine kinase

UniProt annotation for PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Mostly expressed in inflorescence bolt, flower buds and siliques, and, to a lower extent, in roots, seedlings and leaves.

UniProt features for PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1
CHAIN 1 652 Proline-rich receptor-like protein kinase PERK1.
DOMAIN 280 559 Protein kinase.
ACT_SITE 404 404 Proton acceptor (By similarity).
Amino Acid Sequence for PERK1_ARATH » Proline-rich receptor-like protein kinase PERK1
MSTAPSPGTT PSPSPPSPPT NSTTTTPPPA ASSPPPTTTP SSPPPSPSTN STSPPPSSPL PPSLPPPSPP GSLTPPLPQP SPSAPITPSP PSPTTPSNPR SPPSPNQGPP NTPSGSTPRT PSNTKPSPPS DSSDGLSTGV VVGIAIGGVA ILVILTLICL LCKKKRRRRH DDEAAYYVPP PPPSGPKAGG PYGGQQQYWQ QQNASRPSDN HVVTSLPPPK PPSPPRKPPP PPPPPAFMSS SGGSDYSDLP VLPPPSPGLV LGFSKSTFTY EELSRATNGF SEANLLGQGG FGYVHKGILP SGKEVAVKQL KAGSGQGERE FQAEVEIISR VHHRHLVSLI GYCMAGVQRL LVYEFVPNNN LEFHLHGKGR PTMEWSTRLK IALGSAKGLS YLHEDCNPKI IHRDIKASNI LIDFKFEAKV ADFGLAKIAS DTNTHVSTRV MGTFGYLAPE YAASGKLTEK SDVFSFGVVL LELITGRRPV DANNVYVDDS LVDWARPLLN RASEEGDFEG LADSKMGNEY DREEMARMVA CAAACVRHSA RRRPRMSQIV RALEGNVSLS DLNEGMRPGH SNVYSSYGGS TDYDTSQYND DMIKFRKMAL GTQEYGTTGE YSNPTSDYGL YPSGSSSEGQ ATREMEMGKI KKTGQGYSGP SL