PEPR2_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR2

PEPR2_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PEPR2_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR2 » Elicitor peptide 1 receptor 2;PEP1 receptor 2;
Hydrophobic Thickness 41.6 ± 4.8 Å
Tilt Angle 4 ± 2°
ΔGtransfer -23.4 kcal/mol
ΔGfold -22.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 735-762 (735-765)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BAK1, Complex: BAK1:PEPR2

Domains

AA: 27-72, PDBID: 4M7E, Subunit D, Seq Identity:35%, Leucine rich repeat N-terminal domain

AA: 125-147, PDBID: 4MN8, Subunit A, Seq Identity:50%, Leucine Rich Repeat

AA: 292-352, PDBID: 4MN8, Subunit A, Seq Identity:44%, Leucine rich repeat

AA: 484-543, PDBID: 4MN8, Subunit A, Seq Identity:48%, Leucine rich repeat

AA: 794-1073, PDBID: 2HW6, Subunit B, Seq Identity:35%, Protein kinase domain

UniProt annotation for PEPR2_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR2
FUNCTION: Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP-inducible plant responses (By similarity).

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Interacts with BAK1.

UniProt features for PEPR2_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR2
SIGNAL 1 26 Potential.
CHAIN 27 1088 Leucine-rich repeat receptor-like protein kinase PEPR2.
REPEAT 75 99 LRR 1.
REPEAT 100 122 LRR 2.
REPEAT 123 146 LRR 3.
REPEAT 147 170 LRR 4.
REPEAT 172 194 LRR 5.
REPEAT 195 219 LRR 6.
REPEAT 221 243 LRR 7.
REPEAT 244 267 LRR 8.
REPEAT 269 291 LRR 9.
REPEAT 292 315 LRR 10.
REPEAT 316 339 LRR 11.
REPEAT 341 363 LRR 12.
REPEAT 365 387 LRR 13.
REPEAT 388 411 LRR 14.
REPEAT 412 435 LRR 15.
REPEAT 436 459 LRR 16.
REPEAT 460 485 LRR 17.
REPEAT 487 506 LRR 18.
REPEAT 507 529 LRR 19.
REPEAT 530 554 LRR 20.
REPEAT 556 577 LRR 21.
REPEAT 578 602 LRR 22.
REPEAT 603 627 LRR 23.
REPEAT 629 651 LRR 24.
REPEAT 652 676 LRR 25.
REPEAT 678 698 LRR 26.
DOMAIN 794 1080 Protein kinase.
ACT_SITE 921 921 Proton acceptor (By similarity).
Amino Acid Sequence for PEPR2_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR2
MRNLGLLEIT LLCSLFVYFR IDSVSSLNSD GLALLSLLKH FDKVPLEVAS TWKENTSETT PCNNNWFGVI CDLSGNVVET LNLSASGLSG QLGSEIGELK SLVTLDLSLN SFSGLLPSTL GNCTSLEYLD LSNNDFSGEV PDIFGSLQNL TFLYLDRNNL SGLIPASVGG LIELVDLRMS YNNLSGTIPE LLGNCSKLEY LALNNNKLNG SLPASLYLLE NLGELFVSNN SLGGRLHFGS SNCKKLVSLD LSFNDFQGGV PPEIGNCSSL HSLVMVKCNL TGTIPSSMGM LRKVSVIDLS DNRLSGNIPQ ELGNCSSLET LKLNDNQLQG EIPPALSKLK KLQSLELFFN KLSGEIPIGI WKIQSLTQML VYNNTLTGEL PVEVTQLKHL KKLTLFNNGF YGDIPMSLGL NRSLEEVDLL GNRFTGEIPP HLCHGQKLRL FILGSNQLHG KIPASIRQCK TLERVRLEDN KLSGVLPEFP ESLSLSYVNL GSNSFEGSIP RSLGSCKNLL TIDLSQNKLT GLIPPELGNL QSLGLLNLSH NYLEGPLPSQ LSGCARLLYF DVGSNSLNGS IPSSFRSWKS LSTLVLSDNN FLGAIPQFLA ELDRLSDLRI ARNAFGGKIP SSVGLLKSLR YGLDLSANVF TGEIPTTLGA LINLERLNIS NNKLTGPLSV LQSLKSLNQV DVSYNQFTGP IPVNLLSNSS KFSGNPDLCI QASYSVSAII RKEFKSCKGQ VKLSTWKIAL IAAGSSLSVL ALLFALFLVL CRCKRGTKTE DANILAEEGL SLLLNKVLAA TDNLDDKYII GRGAHGVVYR ASLGSGEEYA VKKLIFAEHI RANQNMKREI ETIGLVRHRN LIRLERFWMR KEDGLMLYQY MPNGSLHDVL HRGNQGEAVL DWSARFNIAL GISHGLAYLH HDCHPPIIHR DIKPENILMD SDMEPHIGDF GLARILDDST VSTATVTGTT GYIAPENAYK TVRSKESDVY SYGVVLLELV TGKRALDRSF PEDINIVSWV RSVLSSYEDE DDTAGPIVDP KLVDELLDTK LREQAIQVTD LALRCTDKRP ENRPSMRDVV KDLTDLESFV RSTSGSVH