PEPR1_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR1

PEPR1_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PEPR1_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR1 » Elicitor peptide 1 receptor 1;PEP1 receptor 1;
Hydrophobic Thickness 39.6 ± 3.8 Å
Tilt Angle 0 ± 4°
ΔGtransfer -32.7 kcal/mol
ΔGfold -29.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 768-793 (767-797)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BAK1, Complex: BAK1:PEPR1

Domains

AA: 29-72, PDBID: 4M7E, Subunit D, Seq Identity:39%, Leucine rich repeat N-terminal domain

AA: 99-159, PDBID: 4M7E, Subunit C, Seq Identity:44%, Leucine rich repeat

AA: 123-183, PDBID: 4MN8, Subunit A, Seq Identity:44%, Leucine rich repeat

AA: 460-482, PDBID: 4MN8, Subunit A, Seq Identity:41%, Leucine Rich Repeat

AA: 827-1107, PDBID: 4OA2, Subunit A, Seq Identity:35%, Protein kinase domain

UniProt annotation for PEPR1_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR1
FUNCTION: Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP-inducible plant responses.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Interacts with PEP1 and BAK1.

UniProt features for PEPR1_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR1
SIGNAL 1 28 Potential.
CHAIN 29 1123 Leucine-rich repeat receptor-like protein kinase PEPR1.
REPEAT 31 53 LRR 1.
REPEAT 74 98 LRR 2.
REPEAT 99 122 LRR 3.
REPEAT 124 145 LRR 4.
REPEAT 146 170 LRR 5.
REPEAT 171 194 LRR 6.
REPEAT 196 218 LRR 7.
REPEAT 219 243 LRR 8.
REPEAT 245 266 LRR 9.
REPEAT 267 290 LRR 10.
REPEAT 292 314 LRR 11.
REPEAT 315 338 LRR 12.
REPEAT 340 362 LRR 13.
REPEAT 363 386 LRR 14.
REPEAT 388 410 LRR 15.
REPEAT 412 434 LRR 16.
REPEAT 435 458 LRR 17.
REPEAT 459 482 LRR 18.
REPEAT 484 505 LRR 19.
REPEAT 506 529 LRR 20.
REPEAT 530 553 LRR 21.
REPEAT 554 577 LRR 22.
REPEAT 579 600 LRR 23.
REPEAT 601 625 LRR 24.
REPEAT 626 650 LRR 25.
REPEAT 652 674 LRR 26.
REPEAT 675 696 LRR 27.
REPEAT 697 721 LRR 28.
DOMAIN 827 1115 Protein kinase.
ACT_SITE 954 954 Proton acceptor (By similarity).
Amino Acid Sequence for PEPR1_ARATH » Leucine-rich repeat receptor-like protein kinase PEPR1
MKNLGGLFKI LLLFFCLFLS THIISVSCLN SDGLTLLSLL KHLDRVPPQV TSTWKINASE ATPCNWFGIT CDDSKNVASL NFTRSRVSGQ LGPEIGELKS LQILDLSTNN FSGTIPSTLG NCTKLATLDL SENGFSDKIP DTLDSLKRLE VLYLYINFLT GELPESLFRI PKLQVLYLDY NNLTGPIPQS IGDAKELVEL SMYANQFSGN IPESIGNSSS LQILYLHRNK LVGSLPESLN LLGNLTTLFV GNNSLQGPVR FGSPNCKNLL TLDLSYNEFE GGVPPALGNC SSLDALVIVS GNLSGTIPSS LGMLKNLTIL NLSENRLSGS IPAELGNCSS LNLLKLNDNQ LVGGIPSALG KLRKLESLEL FENRFSGEIP IEIWKSQSLT QLLVYQNNLT GELPVEMTEM KKLKIATLFN NSFYGAIPPG LGVNSSLEEV DFIGNKLTGE IPPNLCHGRK LRILNLGSNL LHGTIPASIG HCKTIRRFIL RENNLSGLLP EFSQDHSLSF LDFNSNNFEG PIPGSLGSCK NLSSINLSRN RFTGQIPPQL GNLQNLGYMN LSRNLLEGSL PAQLSNCVSL ERFDVGFNSL NGSVPSNFSN WKGLTTLVLS ENRFSGGIPQ FLPELKKLST LQIARNAFGG EIPSSIGLIE DLIYDLDLSG NGLTGEIPAK LGDLIKLTRL NISNNNLTGS LSVLKGLTSL LHVDVSNNQF TGPIPDNLEG QLLSEPSSFS GNPNLCIPHS FSASNNSRSA LKYCKDQSKS RKSGLSTWQI VLIAVLSSLL VLVVVLALVF ICLRRRKGRP EKDAYVFTQE EGPSLLLNKV LAATDNLNEK YTIGRGAHGI VYRASLGSGK VYAVKRLVFA SHIRANQSMM REIDTIGKVR HRNLIKLEGF WLRKDDGLML YRYMPKGSLY DVLHGVSPKE NVLDWSARYN VALGVAHGLA YLHYDCHPPI VHRDIKPENI LMDSDLEPHI GDFGLARLLD DSTVSTATVT GTTGYIAPEN AFKTVRGRES DVYSYGVVLL ELVTRKRAVD KSFPESTDIV SWVRSALSSS NNNVEDMVTT IVDPILVDEL LDSSLREQVM QVTELALSCT QQDPAMRPTM RDAVKLLEDV KHLARSCSSD SVR