PEK12_ARATH » Proline-rich receptor-like protein kinase PERK12

PEK12_ARATH » Proline-rich receptor-like protein kinase PERK12
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PEK12_ARATH » Proline-rich receptor-like protein kinase PERK12 » Proline-rich extensin-like receptor kinase 12;AtPERK12; Protein INFLORESCENCE GROWTH INHIBITOR 1;
Hydrophobic Thickness 35.6 ± 2.6 Å
Tilt Angle 3 ± 3°
ΔGtransfer -48.9 kcal/mol
ΔGfold -20.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 244-268 (242-272)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 371-644, PDBID: 2NRU, Subunit B, Seq Identity:45%, Protein tyrosine kinase

UniProt annotation for PEK12_ARATH » Proline-rich receptor-like protein kinase PERK12
FUNCTION: Regulates the auxin-related MAX (More Axillary Growth) pathway during the shoot branching.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Mostly expressed in apical parts, including flower buds, and particularly in anthers. Also present in root hairs.

INDUCTION: Repressed by auxin (IAA) treatment.

UniProt features for PEK12_ARATH » Proline-rich receptor-like protein kinase PERK12
CHAIN 1 720 Proline-rich receptor-like protein kinase PERK12.
DOMAIN 371 624 Protein kinase.
ACT_SITE 495 495 Proton acceptor (By similarity).
Amino Acid Sequence for PEK12_ARATH » Proline-rich receptor-like protein kinase PERK12
MSDLGESPSS SPPAPPADTA PPPETPSENS ALPPVDSSPP SPPADSSSTP PLSEPSTPPP DSQLPPLPSI LPPLTDSPPP PSDSSPPVDS TPSPPPPTSN ESPSPPEDSE TPPAPPNESN DNNPPPSQDL QSPPPSSPSP NVGPTNPESP PLQSPPAPPA SDPTNSPPAS PLDPTNPPPI QPSGPATSPP ANPNAPPSPF PTVPPKTPSS GPVVSPSLTS PSKGTPTPNQ GNGDGGGGGG GYQGKTMVGM AVAGFAIMAL IGVVFLVRRK KKRNIDSYNH SQYLPHPNFS VKSDGFLYGQ DPGKGYSSGP NGSMYNNSQQ QQSSMGNSYG TAGGGYPHHQ MQSSGTPDSA ILGSGQTHFS YEELAEITQG FARKNILGEG GFGCVYKGTL QDGKVVAVKQ LKAGSGQGDR EFKAEVEIIS RVHHRHLVSL VGYCISDQHR LLIYEYVSNQ TLEHHLHGKG LPVLEWSKRV RIAIGSAKGL AYLHEDCHPK IIHRDIKSAN ILLDDEYEAQ VADFGLARLN DTTQTHVSTR VMGTFGYLAP EYASSGKLTD RSDVFSFGVV LLELVTGRKP VDQTQPLGEE SLVEWARPLL LKAIETGDLS ELIDTRLEKR YVEHEVFRMI ETAAACVRHS GPKRPRMVQV VRALDCDGDS GDISNGIKIG QSTTYDSGQY NEDIMKFRKM AFGGDNSVES GLYSGNYSAK SSSDFSGNES ETRPFNNRRF