PCDGD_HUMAN » Protocadherin gamma-B1

PCDGD_HUMAN » Protocadherin gamma-B1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PCDGD_HUMAN » Protocadherin gamma-B1 » PCDH-gamma-B1;
Hydrophobic Thickness 40.8 ± 4.4 Å
Tilt Angle 16 ± 9°
ΔGtransfer -35.1 kcal/mol
ΔGfold -31.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 684-712 (681-715)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 30-109, PDBID: 1WUZ, Subunit A, Seq Identity:45%, Cadherin-like

AA: 135-230, PDBID: 4ZPN, Subunit B, Seq Identity:52%, Cadherin domain

AA: 244-334, PDBID: 2EE0, Subunit A, Seq Identity:43%, Cadherin domain

AA: 348-439, PDBID: 4ZPL, Subunit A, Seq Identity:32%, Cadherin domain

AA: 453-549, PDBID: 2WCP, Subunit A, Seq Identity:33%, Cadherin domain

AA: 573-659, PDBID: 3UBH, Subunit A, Seq Identity:30%, Cadherin domain

AA: 683-765, Cadherin cytoplasmic C-terminal

AA: 805-927, Cadherin C-terminal cytoplasmic tail, catenin-binding region

UniProt annotation for PCDGD_HUMAN » Protocadherin gamma-B1
FUNCTION: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
UniProt features for PCDGD_HUMAN » Protocadherin gamma-B1
SIGNAL 1 28 Potential.
CHAIN 29 927 Protocadherin gamma-B1.
DOMAIN 29 130 Cadherin 1.
DOMAIN 131 239 Cadherin 2.
DOMAIN 240 343 Cadherin 3.
DOMAIN 344 448 Cadherin 4.
DOMAIN 449 558 Cadherin 5.
DOMAIN 566 671 Cadherin 6.
Amino Acid Sequence for PCDGD_HUMAN » Protocadherin gamma-B1
MQRAREAEMM KSQVLFPFLL SLFCGAISQQ IRYTIPEELA NGSRVGKLAK DLGLSVRELP TRKLRVSAED YFNVSLESGD LLVNGRIDRE KICGRKLECA LEFETVAENP MNVFHVVVVI QDINDNAPRF VAKGIDLEIC ESALPGVKFS LDSAQDADVE GNSLKLYTIN PNQYFSLSTK ESPDGSKYPV LLLEKPLDRE HQSSHRLILT AMDGGDPPLS GTTHIWIRVT DANDNAPVFS QEVYRVSLQE NVPWGTSVLR VMATDQDEGI NAEITYAFLN SPISTSLFNL NPNTGDITTN GTLDFEETSR YVLSVEAKDG GVHTAHCNVQ IEIVDENDNA PEVTFMSFSN QIPEDSDLGT VIALIKVRDK DSGQNGMVTC YTQEEVPFKL ESTSKNYYKL VIAGALNREQ TADYNVTIIA TDKGKPALSS RTSITLHISD INDNAPVFHQ ASYVVHVSEN NPPGASIAQV SASDPDLGPN GRVSYSILAS DLEPRELLSY VSVSPQSGVV FAQRAFDHEQ LRAFELTLQA RDQGSPALSA NVSLRVLVGD LNDNAPRVLY PALGPDGSAL FDMVPRAAEP GYLVTKVVAV DADSGHNAWL SYHVLQASEP GLFSLGLRTG EVRTARALGD RDAARQRLLV AVRDGGQPPL SATATLHLIF ADSLQEVLPD LSDRPEPSDP QTELQFYLVV ALALISVLFL LAVILAIALR LRRSSSLDTE GCFQTGLCSK SGPGVPPNHS EGTLPYSYNL CIASHSAKTE FNSLNLTPEM APPQDLLCDD PSMVVCASNE DHKIAYDPSL SSHQAPPNTD WRFSQAQRPG TSGSQNGDDT GTWPNNQFDT EMLQAMILAS ASEAADGSST LGGGAGTMGL SARYGPQFTL QHVPDYRQNV YIPGSNATLT NAAGKRDGKA PAGGNGNKKK SGKKEKK