PCDBI_HUMAN » Putative protocadherin beta-18

PCDBI_HUMAN » Putative protocadherin beta-18
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PCDBI_HUMAN » Putative protocadherin beta-18 » PCDH-beta-18; PCDH-psi2;
Hydrophobic Thickness 38.4 ± 5.8 Å
Tilt Angle 36 ± 3°
ΔGtransfer -27.9 kcal/mol
ΔGfold -22.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 630-662 (627-664)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 3-58, PDBID: 1WYJ, Subunit A, Seq Identity:31%, Cadherin-like

AA: 85-179, PDBID: 4ZPL, Subunit A, Seq Identity:65%, Cadherin domain

AA: 193-286, PDBID: 4ZPL, Subunit A, Seq Identity:40%, Cadherin domain

AA: 299-389, PDBID: 4ZPL, Subunit A, Seq Identity:38%, Cadherin domain

AA: 403-499, PDBID: 4ZPL, Subunit A, Seq Identity:31%, Cadherin domain

AA: 522-610, PDBID: 3UBH, Subunit A, Seq Identity:33%, Cadherin domain

AA: 632-715, Cadherin cytoplasmic C-terminal

UniProt annotation for PCDBI_HUMAN » Putative protocadherin beta-18
FUNCTION: Potential calcium-dependent cell-adhesion protein.
UniProt features for PCDBI_HUMAN » Putative protocadherin beta-18
CHAIN 1 734 Putative protocadherin beta-18.
DOMAIN 1 79 Cadherin 1.
DOMAIN 80 188 Cadherin 2.
DOMAIN 189 293 Cadherin 3.
DOMAIN 294 398 Cadherin 4.
DOMAIN 399 508 Cadherin 5.
DOMAIN 515 621 Cadherin 6.
Amino Acid Sequence for PCDBI_HUMAN » Putative protocadherin beta-18
MWKTWLQGGA RVIFDDYKPY LRLDPQNGDL LLNEQLDREA LCDLTEPCIL HFQVLFENPL QFFRAELLVK DINDHTPTFL NNHMLLKISE GATLGTLFQI DSAQDLDVGK NGVQNYTISP NPHFHLKLRD SDEGRKYPEL VLDQSLDREK VSEFSLTLTA VDGGSPPRSG TTLINVVVLD ISDNAPEFEK PVYEVHVPES SPLDSLIIKA SATDLDAGIN GELSYSFSHV SRDVRKTFEI HPISGEVYLK APLDFEIIQS YIINIQAIEG GSLSGKSSIL VRVVDVNDNP PEIAMTSLTS PIPENSSPEM VVAVFSIRDQ DAGDNGRTVC SIQDNLPFVL KPTFKNFYAL VTEHPLDREV RNEYNITITV TDLGTPRLKT EHNITVLVSD VNDNAPIFTQ TSYTLFVREN NSPALHIGSV SATDRDSGTN AQVTYSLLPP QDPHLPLTSL VSINADNGHL FALRSLDYEA LQEFGFRVGA ADHGSPALSS EVLVRVLVLD ANDNSPFVLY PLQNGSAPCT ELVPRAAEPG YLVTKVVAVD GDSGQNAWLS YQLLKATEPG LFGVWAHNGE GRTARLLSER DAAKHRLVVL VKDNGEPPRS ATATLHVLLV EGFSQPYLPL TEAAPSQAQA DSLTVYLVVA LASVSSLFLF SVFLFVAVRL CRRSRAASMG RCSVPECPFP GHLVDVSGTG TLSQSYQYEV CLTGGSGANE FKFLKPVIPN LLSRDSEMEK APPF