PCDBD_HUMAN » Protocadherin beta-13

PCDBD_HUMAN » Protocadherin beta-13
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PCDBD_HUMAN » Protocadherin beta-13 » PCDH-beta-13;
Hydrophobic Thickness 38.0 ± 4.8 Å
Tilt Angle 40 ± 7°
ΔGtransfer -28.1 kcal/mol
ΔGfold -22.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 683-715 (680-717)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 31-113, PDBID: 1WYJ, Subunit A, Seq Identity:61%, Cadherin-like

AA: 139-234, PDBID: 4ZPL, Subunit A, Seq Identity:59%, Cadherin domain

AA: 248-339, PDBID: 4ZPL, Subunit A, Seq Identity:44%, Cadherin domain

AA: 353-442, PDBID: 4ZPL, Subunit A, Seq Identity:36%, Cadherin domain

AA: 456-552, PDBID: 4ZPL, Subunit A, Seq Identity:31%, Cadherin domain

AA: 575-663, PDBID: 3UBH, Subunit A, Seq Identity:33%, Cadherin domain

AA: 685-768, Cadherin cytoplasmic C-terminal

UniProt annotation for PCDBD_HUMAN » Protocadherin beta-13
FUNCTION: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
UniProt features for PCDBD_HUMAN » Protocadherin beta-13
SIGNAL 1 28 Potential.
CHAIN 29 798 Protocadherin beta-13.
DOMAIN 36 134 Cadherin 1.
DOMAIN 139 243 Cadherin 2.
DOMAIN 248 348 Cadherin 3.
DOMAIN 353 451 Cadherin 4.
DOMAIN 456 561 Cadherin 5.
DOMAIN 568 671 Cadherin 6.
Amino Acid Sequence for PCDBD_HUMAN » Protocadherin beta-13
MEASGKLICR QRQVLFSFLL LGLSLAGAAE PRSYSVVEET EGSSFVTNLA KDLGLEQREF SRRGVRVVSR GNKLHLQLNQ ETADLLLNEK LDREDLCGHT EPCVLRFQVL LESPFEFFQA ELQVIDINDH SPVFLDKQML VKVSESSPPG TTFPLKNAED LDVGQNNIEN YIISPNSYFR VLTRKRSDGR KYPELVLDKA LDREEEAELR LTLTALDGGS PPRSGTAQVY IEVLDVNDNA PEFEQPFYRV QISEDSPVGF LVVKVSATDV DTGVNGEISY SLFQASEEIG KTFKINPLTG EIELKKQLDF EKLQSYEVNI EARDAGTFSG KCTVLIQVID VNDHAPEVTM SAFTSPIPEN APETVVALFS VSDLDSGENG KISCSIQEDL PFLLKSAENF YTLLTERPLD RESRAEYNIT ITVTDLGTPM LITQLNMTVL IADVNDNAPA FTQTSYTLFV RENNSPALHI RSVSATDRDS GTNAQVTYSL LPPQDPHLPL TSLVSINADN GHLFALRSLD YEALQGFQFR VGASDHGSPA LSSEALVRVV VLDANDNSPF VLYPLQNGSA PCTELVPRAA EPGYLVTKVV AVDGDSGQNA WLSYQLLKAT ELGLFGVWAH NGEVRTARLL SERDAAKHRL VVLVKDNGEP PRSATATLHV LLVDGFSQPY LPLPEAAPTQ AQADLLTVYL VVALASVSSL FLFSVLLFVA VRLCRRSRAA SVGRCLVPEG PLPGHLVDMS GTRTLSQSYQ YEVCLAGGSG TNEFKFLKPI IPNFPPQCPG KEIQGNSTFP NNFGFNIQ