PCDBB_HUMAN » Protocadherin beta-11

PCDBB_HUMAN » Protocadherin beta-11
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PCDBB_HUMAN » Protocadherin beta-11 » PCDH-beta-11;
Hydrophobic Thickness 38.4 ± 2.4 Å
Tilt Angle 0 ± 0°
ΔGtransfer -52.8 kcal/mol
ΔGfold -22.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 685-714 (683-720)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 30-112, PDBID: 1WYJ, Subunit A, Seq Identity:60%, Cadherin-like

AA: 139-233, PDBID: 4ZPL, Subunit A, Seq Identity:49%, Cadherin domain

AA: 247-338, PDBID: 4ZPL, Subunit A, Seq Identity:47%, Cadherin domain

AA: 352-442, PDBID: 4ZPL, Subunit A, Seq Identity:37%, Cadherin domain

AA: 456-552, PDBID: 4ZPL, Subunit A, Seq Identity:32%, Cadherin domain

AA: 575-663, PDBID: 3UBH, Subunit A, Seq Identity:33%, Cadherin domain

AA: 685-768, Cadherin cytoplasmic C-terminal

UniProt annotation for PCDBB_HUMAN » Protocadherin beta-11
FUNCTION: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
UniProt features for PCDBB_HUMAN » Protocadherin beta-11
SIGNAL 1 26 Potential.
CHAIN 27 797 Protocadherin beta-11.
DOMAIN 35 133 Cadherin 1.
DOMAIN 138 242 Cadherin 2.
DOMAIN 247 347 Cadherin 3.
DOMAIN 352 451 Cadherin 4.
DOMAIN 456 561 Cadherin 5.
DOMAIN 568 671 Cadherin 6.
Amino Acid Sequence for PCDBB_HUMAN » Protocadherin beta-11
MENQGTRTQQ IRQVLLLFVL LGMSQAGSET WSFSVAEEMQ SGSFVGNLAK DLGLKVRELS SRGARVVSND KKQRLQLDIN TGDLLLSETL DREELCGSIE PCVLHLQVLM QNPTQFLQIE LQVRDINDHS PIFSEKQMLL EIPENSPVGA VFLLESAKDL DVGINAVKSY TISPNSHFHI KMRVIPDNRK YPELVLDKAL DYEELPELSF ILSALDGGSP PRSGTALVRV VVVDINDNSP EFEQAFYEVK IRENSILGSL ILIVSAWDLD SGTNGEICYT FSHASEDIRK TFEINQKSGE ITLRAPLDFE TIESYSIIIQ ATDGGGLFGK STVIIHVIDV NDNAPEITVS SITSPIPENT PETVVMVFSI QDIDSGDNGR IVCSIPEDLP FVLKSSVENY YTLETERPLD RESTAEYNIT ITVTDLGIPR LKTEHNTTVL VSDVNDNAPT FTQTSYTLFV RENNSPALHI GSVSATDRDS GTNAQVNYSL LPPQDLHLPL ASLVSINTDN GHLFALRSLD YEALQAFDFR VGATDRGSPA LSSEALVRVL VLDANDNSPF VLYPLQNGSA PCTELVPRAA EPGYLVTKVV AVDGDSGQNA WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKHRL VVLVKDNGEP PRSATATLQV LLVDGFSQPY LPLPEAAPAQ AQADSLTVYL VVALASVSSL FLFSVLLFVA VRLCRRSRAA SVGSCSVPKG PFPGHLVDVS GTGTLSQSYQ YEVCLTGGSE TNEFKFLKPV IPNIQAKGLG KNSEENSTFR NSFGFNF