PCDB9_HUMAN » Protocadherin beta-9

PCDB9_HUMAN » Protocadherin beta-9
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PCDB9_HUMAN » Protocadherin beta-9 » PCDH-beta-9; Protocadherin-3H;
Hydrophobic Thickness 42.8 ± 2.2 Å
Tilt Angle 0 ± 0°
ΔGtransfer -57.2 kcal/mol
ΔGfold -22.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 682-715 (680-717)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 30-112, PDBID: 1WYJ, Subunit A, Seq Identity:55%, Cadherin-like

AA: 138-233, PDBID: 4ZPL, Subunit A, Seq Identity:57%, Cadherin domain

AA: 247-338, PDBID: 4ZPL, Subunit A, Seq Identity:46%, Cadherin domain

AA: 352-442, PDBID: 4ZPL, Subunit A, Seq Identity:32%, Cadherin domain

AA: 456-552, PDBID: 4ZPL, Subunit A, Seq Identity:32%, Cadherin domain

AA: 575-663, PDBID: 3UBH, Subunit A, Seq Identity:33%, Cadherin domain

AA: 685-768, Cadherin cytoplasmic C-terminal

UniProt annotation for PCDB9_HUMAN » Protocadherin beta-9
FUNCTION: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
UniProt features for PCDB9_HUMAN » Protocadherin beta-9
SIGNAL 1 26 Potential.
CHAIN 27 797 Protocadherin beta-9.
DOMAIN 35 133 Cadherin 1.
DOMAIN 138 242 Cadherin 2.
DOMAIN 247 347 Cadherin 3.
DOMAIN 352 451 Cadherin 4.
DOMAIN 456 561 Cadherin 5.
DOMAIN 568 671 Cadherin 6.
Amino Acid Sequence for PCDB9_HUMAN » Protocadherin beta-9
MKTRGFSFPR QRQVLFLFLF WGVSLAGSGF GRYSVTEETE KGSFVVNLAK DLGLAEGELA ARGTRVVSDD NKQYLLLDSH TGNLLTNEKL DREKLCGPKE PCMLYFQILM DDPFQIYRAE LRVRDINDHS PVFRHKEMVL KISENTAEGT AFRLERAQDP DEGHNSIQNY TISSNSFFHI KISGSDEGMI YPELVLDKAL DREEQEELSL TLTALDGGSP SRSGTSTIRI VVLDVNDNAP QFAQALYETQ APENSPVGSL IVKVSAGDAD SGVNAEVSYS FFDASEDILT TFQINPFSGE IFLRELLDYE LVNSYKINIQ AMDGGGLSAR CTVLIKVLDS NDNPPELIIS SLSNSVAENS PGIVLAVFKI KDRDSGENGK TICYVQDNLP FFLKPSVDNF YILMTEGALD RESKAEYNIT ITVTDLGTPR LKTEHSITLQ VSDVNDNAPA FTQTSYTLFV RENNSPALHI GSVSATDRDS GTNAQVTYSL LPPQDPHLPL ASLVSINADN GHLFALRSLD YEALQAFDFR VGASDRGSPA LSSEALVRVL VLDANDNSPF VLYPLQNGSA PCTELVPRAA EPGYLVTKVV AVDGDSGQNA WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKHRL VVLVKDNGEP PRSATATLHV LLVDGFSQPY LPLPEAAPAQ AQADLLTVYL VVALASVSSL FLLSVLLFVA VRLCRRSRAA SVGRCSVPEG PFPGHLVDVS GTGTLFQSYQ YEVCLTGGSE TGEFKFLKPI TPHLPPHRGG KEIEENSTLP NSFGFNY