PCDB5_HUMAN » Protocadherin beta-5

PCDB5_HUMAN » Protocadherin beta-5
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
PCDB5_HUMAN » Protocadherin beta-5 » PCDH-beta-5;
Hydrophobic Thickness 38.4 ± 2.4 Å
Tilt Angle 0 ± 0°
ΔGtransfer -52.8 kcal/mol
ΔGfold -22.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 684-713 (682-719)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 30-112, PDBID: 1WYJ, Subunit A, Seq Identity:63%, Cadherin-like

AA: 139-233, PDBID: 4ZPL, Subunit A, Seq Identity:64%, Cadherin domain

AA: 247-337, PDBID: 4ZPL, Subunit A, Seq Identity:48%, Cadherin domain

AA: 352-441, PDBID: 4ZPL, Subunit A, Seq Identity:35%, Cadherin domain

AA: 455-551, PDBID: 4ZPL, Subunit A, Seq Identity:32%, Cadherin domain

AA: 574-662, PDBID: 3UBH, Subunit A, Seq Identity:32%, Cadherin domain

AA: 684-767, Cadherin cytoplasmic C-terminal

UniProt annotation for PCDB5_HUMAN » Protocadherin beta-5
FUNCTION: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
UniProt features for PCDB5_HUMAN » Protocadherin beta-5
SIGNAL 1 30 Potential.
CHAIN 31 795 Protocadherin beta-5.
DOMAIN 35 133 Cadherin 1.
DOMAIN 138 242 Cadherin 2.
DOMAIN 247 346 Cadherin 3.
DOMAIN 351 450 Cadherin 4.
DOMAIN 455 560 Cadherin 5.
DOMAIN 567 670 Cadherin 6.
Amino Acid Sequence for PCDB5_HUMAN » Protocadherin beta-5
METALAKTPQ KRQVMFLAIL LLLWEAGSEA VRYSIPEETE SGYSVANLAK DLGLGVGELA TRGARMHYKG NKELLQLDIK TGNLLLYEKL DREVMCGATE PCILHFQLLL ENPVQFFQTD LQLTDINDHA PEFPEKEMLL KIPESTQPGT VFPLKIAQDF DIGSNTVQNY TISPNSHFHV ATHNRGDGRK YPELVLDKAL DREERPELSL TLTALDGGAP PRSGTTTIRI VVLDNNDNAP EFLQSFYEVQ VPENSPLNSL VVVVSARDLD AGAYGSVAYA LFQGDEVTQP FVIDEKTAEI RLKRALDFEA TPYYNVEIVA TDGGGLSGKC TVAIEVVDVN DNAPELTMST LSSPTPENAP ETVVAVFSVS DPDSGDNGRM ICSIQNDLPF LLKPTLKNFY TLVTQRTLDR ESQAEYNITI TVTDMGTPRL KTEHNITVLV SDVNDNAPAF TQTSYTLFVR ENNSPALHIG SVSATDRDSG TNAQVTYSLL PPQNPHLRLA SLVSINADNG HLFALRSLDY EALQAFEFRV GATDRGSPAL SSEALVRVLV LDANDNSPFV LYPLQNGSAP CTELVPRAAE PGYLVTKVVA VDGDSGQNAW LSYQLLKATE PGLFSMWAHN GEVRTARLLS ERDAAKHRLV VLVKDNGEPP RSATATLHVL LVDGFSQPYL PLPEAAPAQA QADSLTVYLV VALASVSSLF LFSVLLFVAV RLCRRSRAAS VGRCSVPEGP FPGHLVDVSG TGTLSQSYHY EVCLTGDSGA GEFKFLKPII PNLLPQGAGE EIGKTAAFRN SFGLN