OPY2_YEAST » Protein OPY2

OPY2_YEAST » Protein OPY2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
OPY2_YEAST » Protein OPY2 » Overproduction-induced pheromone-resistant protein 2;
Hydrophobic Thickness 37.2 ± 2.4 Å
Tilt Angle 1 ± 2°
ΔGtransfer -45.8 kcal/mol
ΔGfold -18.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 91-115 (86-117)
Pathways none
PDB none
OPM none
Complexes none
Interactions

ANP1, Complex: OPY2:ANP1

HKR1, Complex: HKR1:OPY2

HOC1, Complex: HOC1:OPY2

HUR1, Complex: HUR1:OPY2

KEX1, Complex: KEX1:OPY2, PubMed

MNN10, Complex: MNN10:OPY2

MNN11, Complex: MNN11:OPY2

MSB2, Complex: MSB2:OPY2

SEC66, Complex: OPY2:SEC66

Domains

AA: 30-63, Opy2 protein

UniProt annotation for OPY2_YEAST » Protein OPY2
FUNCTION: Component of the high-osmolarity glycerol (HOG) pathway involved in mating response and osmotolerance. May act as a membrane anchor for the STE50/STE11 complex.

MISCELLANEOUS: Present with 1160 molecules/cell in log phase SD medium.

UniProt features for OPY2_YEAST » Protein OPY2
CHAIN 1 360 Protein OPY2.
REGION 266 345 STE50-binding.
Amino Acid Sequence for OPY2_YEAST » Protein OPY2
MSSSSKASAS SSLSSTATSS TSATRGSDGC VVCDSTASCP VCASGEYCVM TSLTCDKCPS TYCAKQSDSQ LSSLSSSSSS SSSSNSNEKT SLIVGFTVGI VGGAMLIALV ALYFINKRYW KPKRQKNKAL KLEEASQSYG NEEEYFDDED DDDEDDEDDG GMRKDESHTL FNTSLVPPTL NVPGNRSSAS TTRTRASNIL PIAYIPGVTS GLSTDKLQSK LRSSSKRQNA AGDIRSHITL GSSILDGLDD EDDEHNQVLN KDADDNLITA IRAKPKLVQI AEEESDKEIQ DLDVIEEQTE ADDLSHMAKS EASHGNNDED DDEEGSFILD LEIPESIRES TQGSRTESPF EDKFEIHDER