OGFD3_HUMAN » 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

OGFD3_HUMAN » 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
OGFD3_HUMAN » 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 »
Hydrophobic Thickness 31.2 ± 2.6 Å
Tilt Angle 0 ± 0°
ΔGtransfer -17.3 kcal/mol
ΔGfold -9.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 43-64 (42-64)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 214-306, PDBID: 2G19, Subunit A, Seq Identity:28%, 2OG-Fe(II) oxygenase superfamily

UniProt annotation for OGFD3_HUMAN » 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
COFACTOR: Binds 1 Fe(2+) ion per subunit (By similarity).
COFACTOR: Ascorbate (By similarity).
UniProt features for OGFD3_HUMAN » 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
CHAIN 1 319 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3.
DOMAIN 207 309 Fe2OG dioxygenase.
ACT_SITE 298 298 Potential.
Amino Acid Sequence for OGFD3_HUMAN » 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
MAPQRRAATK APEGNGAAER RNRSSTKKDR APREVQRLWQ RPWLRTAGLG AGFVLTALLL WSSLGADDGV AEVLARRGEV VAGRFIEVPC SEDYDSHRRF EGCTPRKCGR GVTDVVITRE EAERIRSVAE KGLSLGGSDG GASILDLHSG ALSVGKHFVN LYRYFGDKIQ NIFSEEDFRL YREVRQKVQL TIAEAFGISA SSLHLTKPTF FSRINSTEAR TAHDEYWHAH VDKVTYGSFD YTSLLYLSNY LEDFGGGRFM FMEEGANKTV EPRAGRVSFF TSGSENLHRV EKVHWGTRYA ITIAFSCNPD HGIEDPAFP