NKG2F_HUMAN » NKG2-F type II integral membrane protein

NKG2F_HUMAN » NKG2-F type II integral membrane protein
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
NKG2F_HUMAN » NKG2-F type II integral membrane protein » NK cell receptor F;NKG2-F-activating NK receptor;
Hydrophobic Thickness 33.6 ± 5.0 Å
Tilt Angle 32 ± 1°
ΔGtransfer -23.3 kcal/mol
ΔGfold -12.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 73- 99 (73-102)
Pathways

Antigen processing and presentation (KEGG)

PDB none
OPM none
Complexes none
Interactions

MICB, Complex: NKG2F:MICB, PubMed

RET1G, Complex: NKG2F:RET1G, PubMed

TYOBP, Complex: NKG2F:TYOBP, PubMed

Domains none
UniProt annotation for NKG2F_HUMAN » NKG2-F type II integral membrane protein
FUNCTION: May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.

SUBUNIT: Can form disulfide-bonded heterodimer with CD94.

TISSUE SPECIFICITY: Natural killer cells.

UniProt features for NKG2F_HUMAN » NKG2-F type II integral membrane protein
CHAIN 1 158 NKG2-F type II integral membrane protein.
Amino Acid Sequence for NKG2F_HUMAN » NKG2-F type II integral membrane protein
MNKQRGTYSE VSLAQDPKRQ QRKLKGNKSS ISGTKQEIFQ VELNLQNASS DHQGNDKTYH CKGLLPPPEK LTAEVLGIIC IVLMATVLKT IVLIPCIGVL EQNSFSLNRR MQKARHCGHC PEEWITYSNS CYYIGKERRT WEERVCWPVL RRTLICFL