NCB5R_DICDI » NADH-cytochrome b5 reductase 1

NCB5R_DICDI » NADH-cytochrome b5 reductase 1
Magnify NCB5R_DICDI » NADH-cytochrome b5 reductase 1Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Mitochondrial outer membrane
Topologyintermembrane space
cytoplasmic side
NCB5R_DICDI » NADH-cytochrome b5 reductase 1 »
Hydrophobic Thickness 33.6 ± 2.1 Å
Tilt Angle 1 ± 1°
ΔGtransfer -17.3 kcal/mol
ΔGfold -10.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 5-26 (5-30)
Pathways

Amino sugar and nucleotide sugar metabolism (KEGG)

Biosynthesis of secondary metabolites (KEGG)

PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 56-154, PDBID: 1NDH, Subunit A, Seq Identity:51%, Oxidoreductase FAD-binding domain

AA: 164-270, PDBID: 1UMK, Subunit A, Seq Identity:53%, Oxidoreductase NAD-binding domain

UniProt annotation for NCB5R_DICDI » NADH-cytochrome b5 reductase 1
FUNCTION: Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity).

CATALYTIC ACTIVITY: NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5.

SUBUNIT: Monomer.

UniProt features for NCB5R_DICDI » NADH-cytochrome b5 reductase 1
CHAIN 1 286 NADH-cytochrome b5 reductase 1.
DOMAIN 52 155 FAD-binding FR-type.
Amino Acid Sequence for NCB5R_DICDI » NADH-cytochrome b5 reductase 1
MQISDFILVI IGSVALAAGV KYVFTLTSGS NKDKKGGEAE KGKQVEKALD PQEYRKFQLK EKFIVNHNTR IFRFALPNED DILGLPIGQH ISLRAVVGGK EVYRPYTPIS SDEERGYFDL LIKVYEKGAM SGYVDNMFIG DSIEVKGPKG KFNYQPNMRK SIGMLAGGTG ITPMLQVIKA ILKNPSDKTE ISLVFGNITE EDILLKKELD ELAEKHPQFK VYYVLNNPPK GWTQGVGFVS KEIIESRLPS PSDQTMVIMC GPPMMNKAMT GHLETIGFNE SNIFTF