MXRA8_HUMAN » Matrix-remodeling-associated protein 8

MXRA8_HUMAN » Matrix-remodeling-associated protein 8
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
MXRA8_HUMAN » Matrix-remodeling-associated protein 8 » Limitrin;
Hydrophobic Thickness 30.4 ± 4.2 Å
Tilt Angle 36 ± 5°
ΔGtransfer -30.7 kcal/mol
ΔGfold -26.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 338-363 (332-367)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 37-157, PDBID: 1PKO, Subunit A, Seq Identity:23%, Immunoglobulin V-set domain

AA: 169-292, PDBID: 1PY9, Subunit A, Seq Identity:25%, Immunoglobulin V-set domain

UniProt annotation for MXRA8_HUMAN » Matrix-remodeling-associated protein 8
FUNCTION: May play a role in the maturation and maintenance of blood-brain barrier.
UniProt features for MXRA8_HUMAN » Matrix-remodeling-associated protein 8
SIGNAL 1 19 Potential.
CHAIN 20 442 Matrix-remodeling-associated protein 8.
DOMAIN 29 157 Ig-like V-type 1.
DOMAIN 160 288 Ig-like V-type 2.
DISULFID 54 137 By similarity.
DISULFID 186 272 By similarity.
Amino Acid Sequence for MXRA8_HUMAN » Matrix-remodeling-associated protein 8
MALPSRILLW KLVLLQSSAV LLHSGSSVPA AAGSSVVSES AVSWEAGARA VLRCQSPRMV WTQDRLHDRQ RVLHWDLRGP GGGPARRLLD LYSAGEQRVY EARDRGRLEL SASAFDDGNF SLLIRAVEET DAGLYTCNLH HHYCHLYESL AVRLEVTDGP PATPAYWDGE KEVLAVARGA PALLTCVNRG HVWTDRHVEE AQQVVHWDRQ PPGVPHDRAD RLLDLYASGE RRAYGPLFLR DRVAVGADAF ERGDFSLRIE PLEVADEGTY SCHLHHHYCG LHERRVFHLT VAEPHAEPPP RGSPGNGSSH SGAPGPDPTL ARGHNVINVI VPESRAHFFQ QLGYVLATLL LFILLLVTVL LAARRRRGGY EYSDQKSGKS KGKDVNLAEF AVAAGDQMLY RSEDIQLDYK NNILKERAEL AHSPLPAKYI DLDKGFRKEN CK