MSPD2_HUMAN » Motile sperm domain-containing protein 2

MSPD2_HUMAN » Motile sperm domain-containing protein 2
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
MSPD2_HUMAN » Motile sperm domain-containing protein 2 »
Hydrophobic Thickness 31.6 ± 2.2 Å
Tilt Angle 6 ± 19°
ΔGtransfer -24.9 kcal/mol
ΔGfold -21.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 493-515 (485-517)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 89-234, PDBID: 1AUA, Subunit A, Seq Identity:23%, CRAL/TRIO domain

AA: 327-432, PDBID: 1WIC, Subunit A, Seq Identity:96%, MSP (Major sperm protein) domain

UniProt features for MSPD2_HUMAN » Motile sperm domain-containing protein 2
CHAIN 1 518 Motile sperm domain-containing protein 2.
DOMAIN 82 239 CRAL-TRIO.
DOMAIN 327 445 MSP.
Amino Acid Sequence for MSPD2_HUMAN » Motile sperm domain-containing protein 2
MAENHAQNKA KLISETRRRF EAEYVTDKSD KYDARDVERL QQDDNWVESY LSWRHNIVDE TLKMLDESFQ WRKEISVNDL NESSIPRWLL EIGVIYLHGY DKEGNKLFWI RVKYHVKDQK TILDKKKLIA FWLERYAKRE NGKPVTVMFD LSETGINSID MDFVRFIINC FKVYYPKYLS KIVIFDMPWL MNAAFKIVKT WLGPEAVSLL KFTSKNEVQD YVSVEYLPPH MGGTDPFKYS YPPLVDDDFQ TPLCENGPIT SEDETSSKED IESDGKETLE TISNEEQTPL LKKINPTEST SKAEENEKVD SKVKAFKKPL SVFKGPLLHI SPAEELYFGS TESGEKKTLI VLTNVTKNIV AFKVRTTAPE KYRVKPSNSS CDPGASVDIV VSPHGGLTVS AQDRFLIMAA EMEQSSGTGP AELTQFWKEV PRNKVMEHRL RCHTVESSKP NTLTLKDNAF NMSDKTSEDI CLQLSRLLES NRKLEDQVQR CIWFQQLLLS LTMLLLAFVT SFFYLLYS