MRL1_YEAST » Mannose 6-phosphate receptor-like protein 1

MRL1_YEAST » Mannose 6-phosphate receptor-like protein 1
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Topology in Lysosomal membrane
Topologylysosome lumenal side
cytoplasmic side
MRL1_YEAST » Mannose 6-phosphate receptor-like protein 1 »
Hydrophobic Thickness 26.4 ± 1.8 Å
Tilt Angle 0 ± 1°
ΔGtransfer -32.6 kcal/mol
ΔGfold -14.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 236-258 (236-265)
Pathways

Phagosome (KEGG)

PDB none
OPM none
Complexes none
Interactions

ANP1, Complex: MRL1:ANP1

GPI8, Complex: MRL1:GPI8

HOC1, Complex: MRL1:HOC1

MNN10, Complex: MNN10:MRL1

OSTB, Complex: MRL1:OSTB

PMP2, Complex: PMP2:MRL1, PubMed

PPN1, Complex: , PubMed

SCO1, Complex: SCO1:MRL1, PubMed

VPS10, Complex: VPS10:MRL1, PubMed

Domains

AA: 100-240, PDBID: 2LVX, Subunit A, Seq Identity:12%, Glucosidase II beta subunit-like protein

UniProt annotation for MRL1_YEAST » Mannose 6-phosphate receptor-like protein 1
FUNCTION: Sorting receptor involved in the transport of vacuolar enzymes from the Golgi complex to the vacuole. Involved in the delivery and maturation of PEP4 (vacuolar proteinase A) and PRB1 (vacuolar proteinase B).
UniProt features for MRL1_YEAST » Mannose 6-phosphate receptor-like protein 1
SIGNAL 1 23 Potential.
CHAIN 24 381 Mannose 6-phosphate receptor-like protein 1.
Amino Acid Sequence for MRL1_YEAST » Mannose 6-phosphate receptor-like protein 1
MLKRSSLIYL SCVLIITIPI LLHVYNGPGL SHEANEHRAS HKQKRTLANP DKPKSENDED LFCAVTNPVT GSYIDLSQLS STPNKLREGQ KQISGNNKHE SSKTKWSVRG WGYDTNFTLG ICSSPVGEAE SQQLSNLTGA FYVDQLNENN LVSIGDFSTR PALVGGSTAK KLTLKYENGS MCPNGKDKKA TLLNFVCDKE IQSKAQISYI GNLHNCSYFF EVRSIHACPT SNKKNEVNVL GIFIGIFAIF FLVEFAGRRW IYAKLNRHLK NDDELHDISP SLNEQPHWDL IEDGSRWSKF FNGIIKTTRR FTKSLMRSLV RGRNSRQGGI RLRSSPSASS SSLANREFFR DMEAQNEIID SLDINSHTTE SDHPTLADNS V