MPS2_YEAST » Monopolar spindle protein 2

MPS2_YEAST » Monopolar spindle protein 2
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Topology in Nuclear outer membrane
Topologyintermembrane space
cytoplasmic side
MPS2_YEAST » Monopolar spindle protein 2 »
Hydrophobic Thickness 31.2 ± 3.2 Å
Tilt Angle 3 ± 13°
ΔGtransfer -20.9 kcal/mol
ΔGfold -10.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 306-327 (305-334)
Pathways none
PDB none
OPM none
Complexes none
Interactions

CASP, Complex: CASP:MPS2

CUE1, Complex: CUE1:MPS2

MPS3, Complex: MPS2:MPS3, PubMed

UBC6, Complex: UBC6:MPS2

YHO0, Complex: YHO0:MPS2
Domains

AA: 10-386, Monopolar spindle protein 2
UniProt annotation for MPS2_YEAST » Monopolar spindle protein 2
FUNCTION: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.

SUBUNIT: Interacts with BBP1, MPS3, and SPC24.

UniProt features for MPS2_YEAST » Monopolar spindle protein 2
CHAIN 1 387 Monopolar spindle protein 2.
COILED 117 232 Potential.
Amino Acid Sequence for MPS2_YEAST » Monopolar spindle protein 2
MSNGAFDAIF EYAWGQIDKP ISGDFIYGKD LPKLIEIIEN IFQKAQKSGS YELRLPLFSE INKDLFRTFS NTKTFFKIHK EEFDDIFFNL VNHPLREILE NAFIGVDSIP SDFIVSMNLN SPSKFLVENK NKNTEGAGIS TPRKKLTESP IKLLSRNNIG KALEVQVEEL KRELTAKQSL LQENERQVSE LKIRLETYQE KYASIQQRFS DLQKARQVED NQNSSRTSDP GSPLVTGIDQ KAILEEFRRR LQRQTDTISF LKDQIRRERG LNCSNDKVSH SKRKHATTDG DGTFKNFISA VPSNIWVKAT IRIIVCFALL AGVLPYIRKY VYAHDTPSQN SRLQLSWWEN SGILSKIVWF FEDQTDLETE YRSNANVDDA YSRVFGI