MOXD1_HUMAN » DBH-like monooxygenase protein 1

MOXD1_HUMAN » DBH-like monooxygenase protein 1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
MOXD1_HUMAN » DBH-like monooxygenase protein 1 » Monooxygenase X;
Hydrophobic Thickness 27.6 ± 2.1 Å
Tilt Angle 1 ± 1°
ΔGtransfer -14.2 kcal/mol
ΔGfold -7.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 592-610 (592-612)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 33-148, DOMON domain

AA: 187-315, PDBID: 1OPM, Subunit A, Seq Identity:28%, Copper type II ascorbate-dependent monooxygenase, N-terminal domain

AA: 334-491, PDBID: 1OPM, Subunit A, Seq Identity:22%, Copper type II ascorbate-dependent monooxygenase, C-terminal domain

UniProt annotation for MOXD1_HUMAN » DBH-like monooxygenase protein 1
TISSUE SPECIFICITY: Highly expressed in lung, kidney, brain and spinal cord.

DEVELOPMENTAL STAGE: Expressed in fetal liver and fetal brain.

INDUCTION: By replicative senescence.

UniProt features for MOXD1_HUMAN » DBH-like monooxygenase protein 1
SIGNAL 1 19 Potential.
CHAIN 20 613 DBH-like monooxygenase protein 1.
DOMAIN 35 148 DOMON.
ACT_SITE 203 203 Potential.
ACT_SITE 389 389 Potential.
DISULFID 205 257 By similarity.
DISULFID 242 269 By similarity.
DISULFID 364 480 By similarity.
DISULFID 368 550 By similarity.
DISULFID 443 465 By similarity.
Amino Acid Sequence for MOXD1_HUMAN » DBH-like monooxygenase protein 1
MCCWPLLLLW GLLPGTAAGG SGRTYPHRTL LDSEGKYWLG WSQRGSQIAF RLQVRTAGYV GFGFSPTGAM ASADIVVGGV AHGRPYLQDY FTNANRELKK DAQQDYHLEY AMENSTHTII EFTRELHTCD INDKSITDST VRVIWAYHHE DAGEAGPKYH DSNRGTKSLR LLNPEKTSVL STALPYFDLV NQDVPIPNKD TTYWCQMFKI PVFQEKHHVI KVEPVIQRGH ESLVHHILLY QCSNNFNDSV LESGHECYHP NMPDAFLTCE TVIFAWAIGG EGFSYPPHVG LSLGTPLDPH YVLLEVHYDN PTYEEGLIDN SGLRLFYTMD IRKYDAGVIE AGLWVSLFHT IPPGMPEFQS EGHCTLECLE EALEAEKPSG IHVFAVLLHA HLAGRGIRLR HFRKGKEMKL LAYDDDFDFN FQEFQYLKEE QTILPGDNLI TECRYNTKDR AEMTWGGLST RSEMCLSYLL YYPRINLTRC ASIPDIMEQL QFIGVKEIYR PVTTWPFIIK SPKQYKNLSF MDAMNKFKWT KKEGLSFNKL VLSLPVNVRC SKTDNAEWSI QGMTALPPDI ERPYKAEPLV CGTSSSSSLH RDFSINLLVC LLLLSCTLST KSL