MLEC_HUMAN » Malectin

MLEC_HUMAN » Malectin
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
MLEC_HUMAN » Malectin »
Hydrophobic Thickness 32.4 ± 3.1 Å
Tilt Angle 0 ± 0°
ΔGtransfer -22.5 kcal/mol
ΔGfold -10.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, Reactome
Topology Out
TM Segments 268-290 (267-291)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 48-208, Di-glucose binding within endoplasmic reticulum

UniProt annotation for MLEC_HUMAN » Malectin
FUNCTION: Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity).
UniProt features for MLEC_HUMAN » Malectin
SIGNAL 1 28 Potential.
CHAIN 29 292 Malectin.
Amino Acid Sequence for MLEC_HUMAN » Malectin
MLGAWAVEGT AVALLRLLLL LLPPAIRGPG LGVAGVAGAA GAGLPESVIW AVNAGGEAHV DVHGIHFRKD PLEGRVGRAS DYGMKLPILR SNPEDQILYQ TERYNEETFG YEVPIKEEGD YVLVLKFAEV YFAQSQQKVF DVRLNGHVVV KDLDIFDRVG HSTAHDEIIP MSIRKGKLSV QGEVSTFTGK LYIEFVKGYY DNPKVCALYI MAGTVDDVPK LQPHPGLEKK EEEEEEEEYD EGSNLKKQTN KNRVQSGPRT PNPYASDNSS LMFPILVAFG VFIPTLFCLC RL