LY9_HUMAN » T-lymphocyte surface antigen Ly-9

LY9_HUMAN » T-lymphocyte surface antigen Ly-9
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LY9_HUMAN » T-lymphocyte surface antigen Ly-9 » Cell surface molecule Ly-9;Lymphocyte antigen 9;
Hydrophobic Thickness 34.4 ± 1.5 Å
Tilt Angle 0 ± 8°
ΔGtransfer -21.3 kcal/mol
ΔGfold -20.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 453-475 (448-481)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 156-226, Immunoglobulin domain

AA: 362-431, Immunoglobulin domain

UniProt annotation for LY9_HUMAN » T-lymphocyte surface antigen Ly-9
FUNCTION: May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.
UniProt features for LY9_HUMAN » T-lymphocyte surface antigen Ly-9
SIGNAL 1 47 Potential.
CHAIN 48 655 T-lymphocyte surface antigen Ly-9.
DOMAIN 48 158 Ig-like V-type 1.
DOMAIN 159 235 Ig-like C2-type 1.
DOMAIN 251 363 Ig-like V-type 2.
DOMAIN 364 452 Ig-like C2-type 2.
DISULFID 172 242 Potential.
DISULFID 178 222 Potential.
DISULFID 377 446 Potential.
DISULFID 383 427 Potential.
Amino Acid Sequence for LY9_HUMAN » T-lymphocyte surface antigen Ly-9
MVAPKSHTDD WAPGPFSSKP QRSQLQIFSS VLQTSLLFLL MGLRASGKDS APTVVSGILG GSVTLPLNIS VDTEIENVIW IGPKNALAFA RPKENVTIMV KSYLGRLDIT KWSYSLCISN LTLNDAGSYK AQINQRNFEV TTEEEFTLFV YEQLQEPQVT MKSVKVSENF SCNITLMCSV KGAEKSVLYS WTPREPHASE SNGGSILTVS RTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRRL RKPKITWSLR HSEDGICRIS LTCSVEDGGN TVMYTWTPLQ KEAVVSQGES HLNVSWRSSE NHPNLTCTAS NPVSRSSHQF LSENICSGPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN TMYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVPPPQQ NDLEIPESPT YENFT