LSR_HUMAN » Lipolysis-stimulated lipoprotein receptor

LSR_HUMAN » Lipolysis-stimulated lipoprotein receptor
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LSR_HUMAN » Lipolysis-stimulated lipoprotein receptor »
Hydrophobic Thickness 32.0 ± 2.4 Å
Tilt Angle 0 ± 0°
ΔGtransfer -45.6 kcal/mol
ΔGfold -22.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 258-282 (258-285)
Pathways none
PDB none
OPM none
Complexes none
Interactions

EGFR, Complex: LSR:EGFR

Domains

AA: 259-306, Lipolysis stimulated receptor (LSR)

UniProt annotation for LSR_HUMAN » Lipolysis-stimulated lipoprotein receptor
FUNCTION: Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity).

SUBUNIT: Homotrimer or homotetramer.

UniProt features for LSR_HUMAN » Lipolysis-stimulated lipoprotein receptor
CHAIN 1 649 Lipolysis-stimulated lipoprotein receptor.
DOMAIN 86 234 Ig-like V-type.
DISULFID 111 218 By similarity.
Amino Acid Sequence for LSR_HUMAN » Lipolysis-stimulated lipoprotein receptor
MQQDGLGVGT RNGSGKGRSV HPSWPWCAPR PLRYFGRDAR ARRAQTAAMA LLAGGLSRGL GSHPAAAGRD AVVFVWLLLS TWCTAPARAI QVTVSNPYHV VILFQPVTLP CTYQMTSTPT QPIVIWKYKS FCRDRIADAF SPASVDNQLN AQLAAGNPGY NPYVECQDSV RTVRVVATKQ GNAVTLGDYY QGRRITITGN ADLTFDQTAW GDSGVYYCSV VSAQDLQGNN EAYAELIVLG RTSGVAELLP GFQAGPIEDW LFVVVVCLAA FLIFLLLGIC WCQCCPHTCC CYVRCPCCPD KCCCPEALYA AGKAATSGVP SIYAPSTYAH LSPAKTPPPP AMIPMGPAYN GYPGGYPGDV DRSSSAGGQG SYVPLLRDTD SSVASEVRSG YRIQASQQDD SMRVLYYMEK ELANFDPSRP GPPSGRVERA MSEVTSLHED DWRSRPSRGP ALTPIRDEEW GGHSPRSPRG WDQEPAREQA GGGWRARRPR ARSVDALDDL TPPSTAESGS RSPTSNGGRS RAYMPPRSRS RDDLYDQDDS RDFPRSRDPH YDDFRSRERP PADPRSHHHR TRDPRDNGSR SGDLPYDGRL LEEAVRKKGS EERRRPHKEE EEEAYYPPAP PPYSETDSQA SRERRLKKNL ALSRESLVV