LRRN3_HUMAN » Leucine-rich repeat neuronal protein 3

LRRN3_HUMAN » Leucine-rich repeat neuronal protein 3
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LRRN3_HUMAN » Leucine-rich repeat neuronal protein 3 » Neuronal leucine-rich repeat protein 3;NLRR-3;
Hydrophobic Thickness 32.4 ± 3.8 Å
Tilt Angle 26 ± 1°
ΔGtransfer -19.7 kcal/mol
ΔGfold -12.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 625-649 (616-650)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 116-176, PDBID: 4U7L, Subunit A, Seq Identity:42%, Leucine rich repeat

AA: 164-221, PDBID: 2ID5, Subunit D, Seq Identity:42%, Leucine rich repeat

AA: 212-272, PDBID: 4BSR, Subunit B, Seq Identity:40%, Leucine rich repeat

AA: 309-370, PDBID: 3ZYI, Subunit A, Seq Identity:40%, Leucine rich repeat

AA: 425-513, PDBID: 2ID5, Subunit D, Seq Identity:31%, Immunoglobulin I-set domain

AA: 525-599, PDBID: 1MFN, Subunit A, Seq Identity:29%, Fibronectin type III domain

UniProt features for LRRN3_HUMAN » Leucine-rich repeat neuronal protein 3
SIGNAL 1 22 Potential.
CHAIN 23 708 Leucine-rich repeat neuronal protein 3.
DOMAIN 23 69 LRRNT.
REPEAT 70 91 LRR 1.
REPEAT 93 114 LRR 2.
REPEAT 117 138 LRR 3.
REPEAT 141 162 LRR 4.
REPEAT 165 186 LRR 5.
REPEAT 189 210 LRR 6.
REPEAT 213 234 LRR 7.
REPEAT 237 258 LRR 8.
REPEAT 261 282 LRR 9.
REPEAT 285 304 LRR 10.
REPEAT 310 332 LRR 11.
REPEAT 335 358 LRR 12.
DOMAIN 368 421 LRRCT.
DOMAIN 421 514 Ig-like C2-type.
DOMAIN 518 611 Fibronectin type-III.
DISULFID 444 496 By similarity.
Amino Acid Sequence for LRRN3_HUMAN » Leucine-rich repeat neuronal protein 3
MKDMPLRIHV LLGLAITTLV QAVDKKVDCP RLCTCEIRPW FTPRSIYMEA STVDCNDLGL LTFPARLPAN TQILLLQTNN IAKIEYSTDF PVNLTGLDLS QNNLSSVTNI NVKKMPQLLS VYLEENKLTE LPEKCLSELS NLQELYINHN LLSTISPGAF IGLHNLLRLH LNSNRLQMIN SKWFDALPNL EILMIGENPI IRIKDMNFKP LINLRSLVIA GINLTEIPDN ALVGLENLES ISFYDNRLIK VPHVALQKVV NLKFLDLNKN PINRIRRGDF SNMLHLKELG INNMPELISI DSLAVDNLPD LRKIEATNNP RLSYIHPNAF FRLPKLESLM LNSNALSALY HGTIESLPNL KEISIHSNPI RCDCVIRWMN MNKTNIRFME PDSLFCVDPP EFQGQNVRQV HFRDMMEICL PLIAPESFPS NLNVEAGSYV SFHCRATAEP QPEIYWITPS GQKLLPNTLT DKFYVHSEGT LDINGVTPKE GGLYTCIATN LVGADLKSVM IKVDGSFPQD NNGSLNIKIR DIQANSVLVS WKASSKILKS SVKWTAFVKT ENSHAAQSAR IPSDVKVYNL THLNPSTEYK ICIDIPTIYQ KNRKKCVNVT TKGLHPDQKE YEKNNTTTLM ACLGGLLGII GVICLISCLS PEMNCDGGHS YVRNYLQKPT FALGELYPPL INLWEAGKEK STSLKVKATV IGLPTNMS