LRRN1_HUMAN » Leucine-rich repeat neuronal protein 1

LRRN1_HUMAN » Leucine-rich repeat neuronal protein 1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
LRRN1_HUMAN » Leucine-rich repeat neuronal protein 1 » Neuronal leucine-rich repeat protein 1;NLRR-1;
Hydrophobic Thickness 38.8 ± 1.2 Å
Tilt Angle 0 ± 1°
ΔGtransfer -45.4 kcal/mol
ΔGfold -19.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 628-653 (625-658)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 119-179, PDBID: 1XCD, Subunit A, Seq Identity:42%, Leucine rich repeat

AA: 215-275, PDBID: 4BSR, Subunit B, Seq Identity:45%, Leucine rich repeat

AA: 426-516, PDBID: 2ID5, Subunit D, Seq Identity:34%, Immunoglobulin I-set domain

UniProt features for LRRN1_HUMAN » Leucine-rich repeat neuronal protein 1
SIGNAL 1 25
CHAIN 26 716 Leucine-rich repeat neuronal protein 1.
DOMAIN 26 72 LRRNT.
REPEAT 73 95 LRR 1.
REPEAT 96 117 LRR 2.
REPEAT 120 141 LRR 3.
REPEAT 144 165 LRR 4.
REPEAT 168 189 LRR 5.
REPEAT 192 213 LRR 6.
REPEAT 216 237 LRR 7.
REPEAT 240 261 LRR 8.
REPEAT 264 285 LRR 9.
REPEAT 313 335 LRR 10.
REPEAT 338 359 LRR 11.
DOMAIN 371 424 LRRCT.
DOMAIN 424 515 Ig-like C2-type.
DOMAIN 522 614 Fibronectin type-III.
DISULFID 447 499 By similarity.
Amino Acid Sequence for LRRN1_HUMAN » Leucine-rich repeat neuronal protein 1
MARMSFVIAA CQLVLGLLMT SLTESSIQNS ECPQLCVCEI RPWFTPQSTY REATTVDCND LRLTRIPSNL SSDTQVLLLQ SNNIAKTVDE LQQLFNLTEL DFSQNNFTNI KEVGLANLTQ LTTLHLEENQ ITEMTDYCLQ DLSNLQELYI NHNQISTISA HAFAGLKNLL RLHLNSNKLK VIDSRWFDST PNLEILMIGE NPVIGILDMN FKPLANLRSL VLAGMYLTDI PGNALVGLDS LESLSFYDNK LVKVPQLALQ KVPNLKFLDL NKNPIHKIQE GDFKNMLRLK ELGINNMGEL VSVDRYALDN LPELTKLEAT NNPKLSYIHR LAFRSVPALE SLMLNNNALN AIYQKTVESL PNLREISIHS NPLRCDCVIH WINSNKTNIR FMEPLSMFCA MPPEYKGHQV KEVLIQDSSE QCLPMISHDS FPNRLNVDIG TTVFLDCRAM AEPEPEIYWV TPIGNKITVE TLSDKYKLSS EGTLEISNIQ IEDSGRYTCV AQNVQGADTR VATIKVNGTL LDGTQVLKIY VKQTESHSIL VSWKVNSNVM TSNLKWSSAT MKIDNPHITY TARVPVDVHE YNLTHLQPST DYEVCLTVSN IHQQTQKSCV NVTTKNAAFA VDISDQETST ALAAVMGSMF AVISLASIAV YFAKRFKRKN YHHSLKKYMQ KTSSIPLNEL YPPLINLWEG DSEKDKDGSA DTKPTQVDTS RSYYMW