|LRK19_ARATH » L-type lectin-domain containing receptor kinase I.9 » LecRK-I.9; LecRK79;|
|Hydrophobic Thickness||37.2 ± 4.4 Å|
|Tilt Angle||19 ± 7°|
|Links||UniProtKB, Pfam, Interpro, iHOP, STRING|
|TM Segments||284-310 (282-314)|
|UniProt annotation for LRK19_ARATH » L-type lectin-domain containing receptor kinase I.9|
|FUNCTION: Essential receptor for extracellular ATP. Binds ATP with high affinity through its extracellular legume-lectin like region. Is required for ATP-induced intracellular calcium response, mitogen-activated protein kinase 3 (MPK3) and MPK6 activation and ATP-induced gene expression. May play a variety of roles in stress resistance. May be involved in protein-protein interactions with RGD motif-containing proteins as potential ligands. Plays probably a structural and signaling role at the plant cell surfaces. FUNCTION: May be involved in protein-protein interactions with RGD motif-containing proteins as potential ligands. Plays probably a structural and signaling role at the plant cell surfaces. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. SUBUNIT: Interacts with RGD motif-containing proteins, suspected to disrupt plasma membrane-cell wall adhesions, via its lectin region. TISSUE SPECIFICITY: Expressed in leaf petioles. INDUCTION: By infection with an avirulent isolate of Phytophtora brassicae. DOMAIN: The legume-lectin like region mediates RGD motif recognition. MISCELLANEOUS: Plants over-expressing LECRK19 have more compact rosettes with smaller and slightly wrinkled leaves, reduced height, accumulate anthocyanin and lignin and show enhanced resistance to the oomycete Phytophtora brassicae (PubMed). Ectopic expression of LECRK19 increases plant response to physical wounding (PubMed).|
|UniProt features for LRK19_ARATH » L-type lectin-domain containing receptor kinase I.9|
SIGNAL 1 21 Potential. |
CHAIN 22 766 L-type lectin-domain containing receptor kinase I.9.
DOMAIN 344 616 Protein kinase.
REGION 24 259 Legume-lectin like.
ACT_SITE 468 468 Proton acceptor (By similarity).
|Amino Acid Sequence for LRK19_ARATH » L-type lectin-domain containing receptor kinase I.9|
|MARWLLQILI ISSLHLSSVS SQQETSFVYE SFLDRQNLYL DKSAIVLPSG LLQLTNASEH QMGHAFHKKP IEFSSSGPLS FSTHFVCALV PKPGFEGGHG IVFVLSPSMD FTHAESTRYL GIFNASTNGS SSYHVLAVEL DTIWNPDFKD IDHNHVGIDV NSPISVAIAS ASYYSDMKGS NESINLLSGN PIQVWVDYEG TLLNVSVAPL EVQKPTRPLL SHPINLTELF PNRSSLFAGF SAATGTAISD QYILWWSFSI DRGSLQRLDI SKLPEVPHPR APHKKVSTLI ILLPVCLAIL VLAVLAGLYF RRRRKYSEVS ETWEKEFDAH RFSYRSLFKA TKGFSKDEFL GKGGFGEVYR GNLPQGREIA VKRVSHNGDE GVKQFVAEVV SMRCLKHRNL VPLFGYCRRK RELLLVSEYM PNGSLDEHLF DDQKPVLSWS QRLVVVKGIA SALWYLHTGA DQVVLHRDVK ASNIMLDAEF HGRLGDFGMA RFHEHGGNAA TTAAVGTVGY MAPELITMGA STGTDVYAFG VFMLEVTCGR RPVEPQLQVE KRHMIKWVCE CWKKDSLLDA TDPRLGGKFV AEEVEMVMKL GLLCSNIVPE SRPTMEQVVL YLNKNLPLPD FSPYTLGIGT FAPVLVDASS LVVSSASWSL SGPSMSSSSP NHSPYAWQST DQPWGQTIDT KNSLHIVAEP EKPSPAVKMV TLPAEDPQSN HSSISSQRVQ PVKREKRRLH QILVAFPWIN KQYFKLGLPK HIVHVSLFFF LQLARL|